Portenoy R K
Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
Neurol Clin. 1989 May;7(2):265-88.
Pain can complicate a diverse group of peripheral neuropathies. A number of potential mechanisms have been proposed, but available data are inadequate to posit any pathogenesis with certainty. In most cases, knowledge of the clinical findings associated with the various syndromes permits an etiologic diagnosis, which, in turn, may suggest a primary therapy. Symptomatic treatment is usually needed, however, and includes a large number of pharmacologic therapies, as well as ancillary physiatric and psychological treatments.
疼痛会使多种周围神经病变复杂化。人们已经提出了一些潜在机制,但现有数据不足以确定任何发病机制。在大多数情况下,了解与各种综合征相关的临床发现有助于做出病因诊断,进而可能提示一种主要治疗方法。然而,通常需要进行对症治疗,包括大量药物治疗以及辅助的物理治疗和心理治疗。