Weiss Gabriel, Santer David, Dumfarth Julia, Pisarik Harald, Harrer Marie Luise, Folkmann Sandra, Mach Markus, Moidl Reinhard, Grabenwoger Martin
Department of Cardiovascular Surgery, Hospital Hietzing, Vienna, Austria
Department of Cardiovascular Surgery, Hospital Hietzing, Vienna, Austria.
Eur J Cardiothorac Surg. 2016 Jan;49(1):118-24. doi: 10.1093/ejcts/ezv044. Epub 2015 Feb 10.
To analyse the clinical outcomes of surgical repair of DeBakey type I and III aortic dissection (AD) by using the frozen elephant trunk (FET) technique, and to evaluate the postoperative behaviour of the residual aorta.
In total, 27 consecutive patients underwent treatment of the thoracic aorta for AD with the FET technique in a tertiary-care hospital in Vienna/Austria between 2005 and 2012, and were enrolled in this case series study. All operations were performed under circulatory arrest and bilateral antegrade cerebral perfusion. During the follow-up, a clinical examination was performed as well as aortic diameters and false lumen (FL) patency evaluated by computed tomography (CT) imaging at following levels: pulmonary bifurcation, diaphragm and coeliac trunk.
The mean age of the patient cohort was 56 ± 12 years; 21 patients were male. Twenty-two (82%) and 5 (18%) patients presented with DeBakey type I and type III AD, respectively. The hospital mortality rate was 7% (2/28); 2 patients died due to non-aortic-related reasons during a follow-up period of 48 ± 26 months. Three (11%) patients had a stroke, and 2 (7%) a spinal cord injury. The follow-up CT scans revealed FL thrombosis in 96% of the patients at the level of the pulmonary bifurcation (P < 0.001). Distal to the stent graft, at the level of the diaphragm and coeliac trunk, FL patency was observed in 52% (P = 0.1) and 78% (P = 0.6) of the patients, respectively. The true lumen of all analysed aortic segments increased significantly while the mean aortic diameter remained stable.
Compared with conventional surgery for extensive ADs, the FET technique provides a high rate of FL thrombosis of the thoracic aorta.
分析采用冰冻象鼻(FET)技术手术修复Ⅰ型和Ⅲ型主动脉夹层(AD)的临床疗效,并评估残余主动脉术后情况。
2005年至2012年期间,在奥地利维也纳一家三级医疗中心,共有27例连续患者采用FET技术治疗胸主动脉AD,并纳入本病例系列研究。所有手术均在循环停止和双侧顺行性脑灌注下进行。随访期间,进行临床检查,并通过计算机断层扫描(CT)成像在以下层面评估主动脉直径和假腔(FL)通畅情况:肺动脉分叉、膈肌和腹腔干。
患者队列的平均年龄为56±12岁;21例为男性。分别有22例(82%)和5例(18%)患者表现为DeBakeyⅠ型和Ⅲ型AD。医院死亡率为7%(2/28);2例患者在48±26个月的随访期内因非主动脉相关原因死亡。3例(11%)患者发生中风,2例(7%)患者发生脊髓损伤。随访CT扫描显示,96%的患者在肺动脉分叉水平出现FL血栓形成(P<0.001)。在支架移植物远端,在膈肌和腹腔干水平,分别有52%(P=0.1)和78%(P=0.6)的患者观察到FL通畅。所有分析的主动脉节段的真腔显著增大,而平均主动脉直径保持稳定。
与广泛AD的传统手术相比,FET技术可使胸主动脉FL血栓形成率较高。