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Cellular origin of prognostic chromosomal aberrations in AML patients.

作者信息

Mora-Jensen H, Jendholm J, Rapin N, Andersen M K, Roug A S, Bagger F O, Bullinger L, Winther O, Borregaard N, Porse B T, Theilgaard-Mönch K

机构信息

The Granulocyte Research Laboratory, Department of Hematology, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

1] The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark [2] Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark [3] Danish Stem Cell Centre (DanStem) Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

出版信息

Leukemia. 2015 Aug;29(8):1785-9. doi: 10.1038/leu.2015.30. Epub 2015 Feb 11.

DOI:10.1038/leu.2015.30
PMID:25670329
Abstract
摘要

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Nature. 2014 Feb 20;506(7488):328-33. doi: 10.1038/nature13038. Epub 2014 Feb 12.
3
Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
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Sci Adv. 2019 Jul 10;5(7):eaaw4304. doi: 10.1126/sciadv.aaw4304. eCollection 2019 Jul.
4
Development and validation of GMI signature based random survival forest prognosis model to predict clinical outcome in acute myeloid leukemia.基于 GMI 特征的随机生存森林预后模型的建立与验证及其在急性髓系白血病患者临床预后评估中的应用。
BMC Med Genomics. 2019 Jun 26;12(1):90. doi: 10.1186/s12920-019-0540-5.
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Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.人类成体 HSCs 可以通过表达内粘蛋白与谱系定向的 HPC 区分开来。
Blood Adv. 2018 Jul 10;2(13):1628-1632. doi: 10.1182/bloodadvances.2018015743.
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Br J Haematol. 2016 Nov;175(3):393-401. doi: 10.1111/bjh.14270. Epub 2016 Sep 9.
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Leukemia. 2016 Apr;30(4):767-75. doi: 10.1038/leu.2015.324. Epub 2015 Nov 25.
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