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选择性脊神经后根切断术:一种再度兴起的古老治疗方法。

Selective dorsal rhizotomy: an old treatment re-emerging.

作者信息

Aquilina Kristian, Graham David, Wimalasundera Neil

机构信息

Department of Neurosurgery, Great Ormond Street Hospital for Children NHS Trust, London, UK.

Faculty of Medicine, University of Sydney, Sydney, Australia.

出版信息

Arch Dis Child. 2015 Aug;100(8):798-802. doi: 10.1136/archdischild-2014-306874. Epub 2015 Feb 10.

Abstract

Selective dorsal rhizotomy (SDR) is a neurosurgical technique developed to reduce spasticity and improve mobility in children with cerebral palsy (CP) and lower extremity spasticity. It involves the selective division of lumbosacral afferent (sensory) rootlets at the conus or at the intervertebral foramina under intraoperative neurophysiological guidance. First described in 1908, early procedures were effective at reducing spasticity but were associated with significant morbidity. Technical advancements over the last two decades have reduced the invasiveness of the procedure, typically from a five-level laminoplasty to a single-level laminotomy at the conus. As practised today, SDR is an effective treatment for young patients with bilateral spastic CP who are rigorously selected for surgery and for whom realistic objectives are set. SDR has therefore re-emerged as a valuable management option for spastic CP. In this article, the authors review the single-level SDR technique and its role in the management of bilateral spastic CP, with particular emphasis on patient selection and outcomes.

摘要

选择性脊神经后根切断术(SDR)是一种神经外科技术,旨在减轻脑瘫(CP)患儿的下肢痉挛并改善其活动能力。该手术在术中神经生理引导下,于圆锥或椎间孔处选择性切断腰骶部传入(感觉)神经根丝。该技术于1908年首次被描述,早期手术虽能有效减轻痉挛,但并发症严重。过去二十年来的技术进步降低了手术的侵入性,通常从五级椎板成形术变为圆锥处的单级椎板切开术。如今,对于经过严格筛选并设定了合理目标的双侧痉挛性脑瘫年轻患者,SDR是一种有效的治疗方法。因此,SDR已重新成为痉挛性脑瘫的一种有价值的治疗选择。在本文中,作者回顾了单级SDR技术及其在双侧痉挛性脑瘫治疗中的作用,特别强调了患者选择和治疗效果。

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