Australian National University College of Health and Medicine, Canberra, Australian Capital Territory, Australia.
The Children's Hospital at Westmead, Westmead, New South Wales, Australia.
BMJ Paediatr Open. 2024 Mar 15;8(1):e002381. doi: 10.1136/bmjpo-2023-002381.
Selective dorsal rhizotomy (SDR) is a neurosurgical procedure that reduces lower limb spasticity, performed in some children with spastic diplegic cerebral palsy. Effective pain management after SDR is essential for early rehabilitation. This study aimed to describe the anaesthetic and early pain management, pain and adverse events in children following SDR.
This was a retrospective cohort study. Participants were all children who underwent SDR at a single Australian tertiary hospital between 2010 and 2020. Electronic medical records of all children identified were reviewed. Data collected included demographic and clinical data (pain scores, key clinical outcomes, adverse events and side effects) and medications used during anaesthesia and postoperative recovery.
22 children (n=8, 36% female) had SDR. The mean (SD) age at surgery was 6 years and 6 months (1 year and 4 months). Common intraoperative medications used were remifentanil (100%), ketamine (95%), paracetamol (91%) and sevoflurane (86%). Postoperatively, all children were prescribed opioid nurse-controlled analgesia (morphine, 36%; fentanyl, 36%; and oxycodone, 18%) and concomitant ketamine infusion. Opioid doses were maximal on the day after surgery. The mean (SD) daily average pain score (Wong-Baker FACES scale) on the day after surgery was 1.4 (0.9), decreasing to 1.0 (0.5) on postoperative day 6 (POD6). Children first attended the physiotherapy gym on median day 7 (POD8, range 7-8). Most children experienced mild side effects or adverse events that were managed conservatively. Common side effects included constipation (n=19), nausea and vomiting (n=18), and pruritus (n=14). No patient required return to theatre, ICU admission or prolonged inpatient stay.
Most children achieve good pain management following SDR with opioid and ketamine infusions. Adverse events, while common, are typically mild and managed with medication or therapy. This information can be used as a baseline to improve postoperative care and to support families' understanding of SDR before surgery.
选择性脊神经后根切断术(SDR)是一种神经外科手术,可降低痉挛性双瘫脑瘫患儿的下肢痉挛程度。SDR 后有效的疼痛管理对早期康复至关重要。本研究旨在描述 SDR 后儿童的麻醉和早期疼痛管理、疼痛和不良事件。
这是一项回顾性队列研究。参与者均为 2010 年至 2020 年在澳大利亚一家三级医院接受 SDR 的儿童。回顾了所有确定的患儿的电子病历。收集的数据包括人口统计学和临床数据(疼痛评分、关键临床结果、不良事件和副作用)以及麻醉和术后恢复期间使用的药物。
22 名儿童(n=8,36%为女性)接受了 SDR。手术时的平均(SD)年龄为 6 岁零 6 个月(1 岁零 4 个月)。术中常用的药物有瑞芬太尼(100%)、氯胺酮(95%)、对乙酰氨基酚(91%)和七氟醚(86%)。术后,所有患儿均开具了阿片类药物护士控制镇痛(吗啡,36%;芬太尼,36%;和羟考酮,18%)和同时给予氯胺酮输注。术后第 1 天的阿片类药物剂量最大。术后第 1 天的平均(SD)每日平均疼痛评分(Wong-Baker FACES 量表)为 1.4(0.9),术后第 6 天(POD6)降至 1.0(0.5)。患儿中位数于术后第 7 天(POD8,范围 7-8)首次到物理治疗健身房就诊。大多数患儿出现轻度副作用或不良事件,经保守治疗后得到缓解。常见的副作用包括便秘(n=19)、恶心和呕吐(n=18)和瘙痒(n=14)。无患儿需要返回手术室、入住 ICU 或延长住院时间。
大多数患儿在 SDR 后使用阿片类药物和氯胺酮输注可实现良好的疼痛管理。不良事件虽然常见,但通常是轻度的,可用药物或治疗来管理。这些信息可以用作改善术后护理的基线,并为术前家属了解 SDR 提供支持。