Panfilov Iu A, Osadchuk M A, Kvetnoĭ I M
Ter Arkh. 1989;61(2):30-2.
Endocrine cells of the duodenal bulb producing adrenalin, noradrenalin, serotonin, histamine and beta-endorphine were assayed in 12 patients with preulcer and 39 patients with duodenal ulcer. It is shown that preulcer was mainly characterized by hyperplasia of endocrine cells in the duodenal bulb mucosa, secreting adrenalin and noradrenalin in the presence of the deficiency of beta-endorphine-producing cells. The recurrent duodenal ulcer was associated with a dramatic fall in the number of catecholamine-containing endocrine cells in the duodenal bulb.
对12例溃疡前期患者和39例十二指肠溃疡患者的十二指肠球部产生肾上腺素、去甲肾上腺素、血清素、组胺和β-内啡肽的内分泌细胞进行了检测。结果表明，溃疡前期主要表现为十二指肠球部黏膜内分泌细胞增生，在产生β-内啡肽的细胞缺乏的情况下分泌肾上腺素和去甲肾上腺素。复发性十二指肠溃疡与十二指肠球部含儿茶酚胺的内分泌细胞数量急剧减少有关。
