Ivanov A S, Petrov V V, Antonov V F
Biofizika. 1978 Mar-Apr;23(2):253-6.
By means of the system of ion-selective electrodes the coupling transport of K+, H+ and Cl- ions in liposome suspension was studied. Nigericin and tributyl tin (TBT) were used as inductors of cation and anion exchange. Effect of pH gradient created on the membrane on ionic transport was studied. The latter was shown to control the antiport exchange of both, cations and anions. At the joint effect of nigericin and TBT the yield of K+ and Cl- ions from liposomes independent of the pH gradient was observed.
通过离子选择性电极系统,研究了脂质体悬浮液中K⁺、H⁺和Cl⁻离子的耦合转运。尼日利亚菌素和三丁基锡(TBT)用作阳离子和阴离子交换的诱导剂。研究了膜上产生的pH梯度对离子转运的影响。结果表明,pH梯度控制阳离子和阴离子的反向转运交换。在尼日利亚菌素和TBT的共同作用下,观察到脂质体中K⁺和Cl⁻离子的释放与pH梯度无关。