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无分流外翻式颈动脉内膜切除术:关于1385例连续病例

Eversion carotid endarterectomy without shunt: concerning 1385 consecutive cases.

作者信息

Ben Ahmed Sabrina, Daniel Guillaume, Benezit Marie, Ribal Jean-Pierre, Rosset Eugenio

机构信息

Department of Vascular Surgery, CHU Clermont-Ferrand, Clermont-Ferrand, France.

Faculty of Medicine, Clermont University, Univ Clermont 1, Clermont-Ferrand, France.

出版信息

J Cardiovasc Surg (Torino). 2017 Aug;58(4):543-550. doi: 10.23736/S0021-9509.16.08495-0. Epub 2015 Feb 12.

Abstract

BACKGROUND

The aim of this study was to evaluate the perioperative results of eversion carotid endarterectomy (e-CEA) without shunt at 30 days.

METHODS

From January 2004 to December 2013, 1385 e-CEAs were performed in 981 men and 404 women, for 268 hemispheric, 55 ocular and 12 oculopyramidal symptoms of carotid stenosis. The average age was 71.1 years. The contralateral internal carotid artery (ICA) was occluded in 77 cases. All e-CEAs were performed using Vanmaele technique, with blood pressure monitoring and under general anesthesia except in two cases (locoregional anesthesia alone). The need for application of an intra-arterial shunt was evaluated using visual quantification of adequate retrograde ICA pressure based on the quality of back-bleeding from the ICA. If well pulsatile, a shunt was not required. Otherwise, the systolic blood pressure was increased until a good quality ICA back-flow was obtained.

RESULTS

Freedom from intra-arterial shunt placement was 100% as a result of estimation and augmentation of arterial perfusion to demonstrate pulsatile perfusion by retrograde ICA filling. A peroperative angiography was performed in 910 cases. All surgical sites were evaluated postoperatively by Duplex imaging. The overall stroke and death rate was 1.3%. Nine (0.7%) patients died perioperatively. The 24 (1.7%) non-fatal neurologic events were ipsilateral: 6 (0.4%) disabling and 9 (0.6%) regressive stroke, 3 (0.2%) permanent and 1 (0.1%) transient ocular ischemia, and 5 (0.4%) transient ischemic attacks. Three (0.2%) patients had a perioperative myocardial infarction. Eleven compressive neck hematomas (0.8%) were reoperated in emergency.

CONCLUSIONS

E-CEA can be performed safely, as a routine technique, based on the surgeon's evaluation of arterial back-bleeding and an increase in ipsilateral arterial perfusion with standard anesthetic procedures. Also e-CEA may be considered a cost effective method of reducing the frequency of intra-arterial shunt placement and adjuncts used to assess adequate cerebral perfusion of the ipsilateral carotid artery during e-CEA.

摘要

背景

本研究旨在评估外翻式颈动脉内膜切除术(e-CEA)在30天时的围手术期结果。

方法

2004年1月至2013年12月,对981名男性和404名女性实施了1385例e-CEA手术,治疗268例半球性、55例眼部及12例眼锥性颈动脉狭窄症状。平均年龄为71.1岁。77例对侧颈内动脉(ICA)闭塞。除2例(仅局部区域麻醉)外,所有e-CEA手术均采用Vanmaele技术,在全身麻醉下进行,并进行血压监测。根据ICA回血质量,通过视觉量化评估ICA逆行压力是否充足来判断是否需要应用动脉内分流管。若回血搏动良好,则无需分流管。否则,升高收缩压直至获得质量良好的ICA回血。

结果

通过评估和增加动脉灌注以显示ICA逆行充盈的搏动性灌注,动脉内分流管放置率为100%。910例患者进行了术中血管造影。术后通过双功超声成像评估所有手术部位。总体卒中与死亡率为1.3%。9例(0.7%)患者围手术期死亡。24例(1.7%)非致命性神经事件为同侧:6例(0.4%)致残性卒中、9例(0.6%)退行性卒中、3例(0.2%)永久性和1例(0.1%)短暂性眼部缺血,以及5例(0.4%)短暂性脑缺血发作。3例(0.2%)患者发生围手术期心肌梗死。11例(0.8%)压迫性颈部血肿患者接受了急诊再次手术。

结论

基于外科医生对动脉回血的评估以及采用标准麻醉程序时同侧动脉灌注的增加,e-CEA作为一种常规技术可安全实施。此外,e-CEA可被视为一种经济有效的方法,可减少动脉内分流管的放置频率以及在e-CEA期间用于评估同侧颈动脉充分脑灌注的辅助手段。

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