Barakat Athar, Grover Karan, Peshin Rohit
Department of Rheumatology, Nobles Hospital, Isle of Man, IM44RJ UK.
Springerplus. 2014 Dec 18;3:751. doi: 10.1186/2193-1801-3-751. eCollection 2014.
We report the case of a patient with Rheumatoid Arthritis [RA] presenting with clinical-pathological and radiological features of Pulmonary Lymphomatoid Granulomatosis (PLG). This is a rare lung disorder characterized by multiple nodular lesions with lymphocytic invasion of vascular walls. We present one such case of PLG secondary to Methotrexate and Azathioprine therapy, who was successfully treated with Steroids and Rituximab. We wish to highlight the importance of lung biopsy in the diagnosis and the use of rituximab as a treatment modality for RA as well as PLG.
我们报告了一例类风湿关节炎（RA）患者，其表现出肺淋巴瘤样肉芽肿病（PLG）的临床病理和放射学特征。这是一种罕见的肺部疾病，其特征为多个结节性病变以及血管壁的淋巴细胞浸润。我们呈现了一例继发于甲氨蝶呤和硫唑嘌呤治疗的PLG病例，该患者通过类固醇和利妥昔单抗成功治愈。我们希望强调肺活检在诊断中的重要性以及利妥昔单抗作为RA和PLG治疗方式的应用。
