Depelchin P, Hammoude H, Degré S
Service de Cardiologie, Hôpital Erasme, Université Libre de Bruxelles, Belgique.
Ann Cardiol Angeiol (Paris). 1989 Mar;38(3):155-61.
Invasive or pharmacological treatments at the onset of a myocardial infarction or a few days later, make it possible to decrease the mortality and morbidity through prevention of the ventricular fibrillation, decrease of the size of the infarction, inhibition of platelet aggregation and other mechanisms. Early administration of betablockers results in a significant decrease of the mortality at one year, in patients undergoing an active treatment. Later treatment also results in decreased coronary mortality and morbidity. This article intends to review the most recent information concerning the potential preventive value of beta-blockers after myocardial infarction.
在心肌梗死发作时或几天后进行侵入性治疗或药物治疗,通过预防心室颤动、减小梗死面积、抑制血小板聚集及其他机制,有可能降低死亡率和发病率。对于正在接受积极治疗的患者,早期给予β受体阻滞剂可使一年时的死亡率显著降低。后期治疗也可降低冠状动脉疾病的死亡率和发病率。本文旨在综述有关心肌梗死后β受体阻滞剂潜在预防价值的最新信息。