Moraes Christopher
Department of Chemical Engineering, McGill University, Montreal, QC, Canada.
Integr Biol (Camb). 2015 Mar;7(3):285-8. doi: 10.1039/c5ib90004b. Epub 2015 Feb 13.
Approaches to drug development have changed significantly over the last decade in response to the continued decline in productivity of the current discovery model. Here, we highlight exciting findings and promising approaches in the recent literature in which researchers integrate advanced micro-engineering, design, and analytical strategies to improve the relevance and utility of high-throughput screening in the drug discovery pipeline.
在过去十年中,由于当前发现模式的生产率持续下降,药物开发方法发生了显著变化。在此,我们重点介绍近期文献中的一些令人兴奋的发现和有前景的方法,研究人员在这些文献中整合了先进的微工程、设计和分析策略,以提高药物发现流程中高通量筛选的相关性和实用性。