Scheinberg Morton, Castañeda-Hernández Gilberto
Arthritis Res Ther. 2014 Dec 6;16(6):501. doi: 10.1186/s13075-014-0501-5.
Biosimilars that were not compared in clinical trials with the compound innovator are not true biosimilars (biocopies) and are associated with risks that the clinical rheumatologist should be aware of before generalized use. This article comments on various aspects surrounding the use of such biocopies in clinical rheumatology.
未在临床试验中与原研化合物进行对比的生物类似药并非真正的生物类似药(生物复制品),且存在一定风险,临床风湿病学家在广泛使用前应予以关注。本文对临床风湿病学中此类生物复制品使用的各个方面进行了评论。