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两个非洲人群中的Y染色体DNA多态性。

Y chromosome DNA polymorphisms in two African populations.

作者信息

Lucotte G, Guérin P, Hallé L, Loirat F, Hazout S

机构信息

Laboratory of Molecular Genetics, INTS, Collège de France, Paris, France.

出版信息

Am J Hum Genet. 1989 Jul;45(1):16-20.

PMID:2568089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1683369/
Abstract

Y chromosome-specific DNA polymorphisms were detected using probe p49f after restriction with TaqI enzyme on samples coming from two African populations: Bantus and Pygmies. All the main TaqI alleles at five Y loci already found in Caucasians are also found in these two populations; 12 of the 16 Caucasian haplotypes were found in these two African populations, and two new haplotypes are Pygmy specific. A proposed phylogeny of the various haplotypes that was derived by using the parsimony criterion established that haplotypes XIII and XVIII, respectively the most frequent one and only one present in Pygmies, are probably ancestral.

摘要

使用探针p49f对来自两个非洲群体(班图人和俾格米人)的样本进行TaqI酶切后,检测Y染色体特异性DNA多态性。在这两个群体中也发现了在高加索人中已发现的五个Y位点上的所有主要TaqI等位基因;在这两个非洲群体中发现了16种高加索单倍型中的12种,并且有两种新的单倍型是俾格米人特有的。通过使用简约标准推导得出的各种单倍型的系统发育树表明,单倍型XIII和XVIII,分别是最常见的和仅在俾格米人中存在的一种,可能是祖先型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa7e/1683369/4647cc55c804/ajhg00104-0024-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa7e/1683369/4647cc55c804/ajhg00104-0024-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa7e/1683369/4647cc55c804/ajhg00104-0024-a.jpg

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Human genetic affinities for Y-chromosome P49a,f/TaqI haplotypes show strong correspondence with linguistics.人类Y染色体P49a,f/TaqI单倍型的遗传亲缘关系与语言学表现出强烈的对应关系。
Am J Hum Genet. 1997 Nov;61(5):1015-35. doi: 10.1086/301602.
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mtDNA and Y-chromosome polymorphisms in four Native American populations from southern Mexico.

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Y chromosome probe p49a detects complex PvuII haplotypes and many new TaqI haplotypes in southern African populations.Y染色体探针p49a在南部非洲人群中检测到复杂的PvuII单倍型和许多新的TaqI单倍型。
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