Feci L, Rubegni P, Nami N Cerroni L, Fimiani M
Dermatology Section, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy -
G Ital Dermatol Venereol. 2015 Feb;150(1):123-6.
We report the case of a 20-year-old woman with one-year history of asymptomatic pink papules on the abdomen, with central atrophy. Fever and symptoms suggesting involvement of other organs were absent. Histological examination revealed wedge-shaped area of cutaneous ischemia extending into the deep dermis with superficial and deep perivascular lymphocytic infiltrate. On this basis, we diagnosed malignant atrophic papulosis. Laboratory tests and instrumental investigation did not reveal any systemic involvement. The rarity of this disease makes early diagnosis challenging, even if clinical and histological patterns of the skin lesions are peculiar.
我们报告了一例20岁女性病例，其腹部出现无症状粉红色丘疹已有一年病史，丘疹中央有萎缩。患者无发热及提示其他器官受累的症状。组织学检查显示，皮肤缺血的楔形区域延伸至真皮深层，伴有浅层和深层血管周围淋巴细胞浸润。在此基础上，我们诊断为恶性萎缩性丘疹病。实验室检查和器械检查未发现任何全身受累情况。尽管该疾病的皮肤病变在临床和组织学上有独特表现，但因其罕见，早期诊断仍具有挑战性。
