Uldry P A, Regli F
Schweiz Rundsch Med Prax. 1989 Jun 6;78(23):671-3.
Toxic myopathies are an uncommon manifestation of chemotherapeutic agents. Most myopathies are characterized by a weakness affecting proximal limb-muscles more than distal ones. Steroids, chloroquine and ipecac syrup are the most common drugs inducing myopathies. Toxic myositis is rare and reported with D-penicillamine abuse. Myotoxicity of local agents injection such as anesthetics, steroids or antibiotics is also known. Congenital myopathies such as malignant hyperthermia, hypokalemic periodic paralysis or paroxysmal myoglobinuria may also be induced by drugs but are very rare.
中毒性肌病是化疗药物罕见的表现形式。大多数肌病的特征是近端肢体肌肉无力比远端更明显。类固醇、氯喹和吐根糖浆是最常见的诱发肌病的药物。中毒性肌炎罕见，有因滥用青霉胺而导致的报道。局部注射麻醉剂、类固醇或抗生素等药物的肌毒性也有相关报道。先天性肌病如恶性高热、低钾性周期性麻痹或阵发性肌红蛋白尿也可能由药物诱发，但非常罕见。
