Suppr超能文献

老年髋部骨折手术后谵妄的防治

The Prevention and Treatment of Delirium in Elderly Patients Following Hip Fracture Surgery.

作者信息

Martocchia Antonio, Curto Martina, Comite Fabrizia, Scaccianoce Sergio, Girardi Paolo, Ferracuti Stefano, Nicoletti Ferdinando, Falaschi Paolo

机构信息

S.Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.

出版信息

Recent Pat CNS Drug Discov. 2015;10(1):55-64. doi: 10.2174/1574889810666150216152624.

Abstract

Osteoporotic hip fracture needs a specific approach and treatment, since elderly patients are at high risk for adverse outcomes after surgery. In particular, delirium often occurs in the peri-operative period, and it is associated with death, hospital-acquired complications, persistent cognitive impairments, poor functional recovery after surgery and increased healthcare costs. The pre-operative assessment of the risk factors for delirium improves the preventive measures. The delirium diagnostic tools should be included in the standard of orthogeriatric cure for hip fracture. Given the increasing complexity of the clinical pictures, we present a review of the available treatment options for delirium in patients with hip fracture. The metabolic pre-operative disorders and the management of co-morbid diseases are specific targets of treatment in order to optimize the outcomes after surgery. In particular, elderly patients with Alzheimer's disease are highly vulnerable to hip fracture and delirium, and they are severely frail with reduced physiologic reserves. An integrated approach combining environmental and pharmacological strategies is useful in the delirium treatment, with a close collaboration between the orthopedic and geriatric team.

摘要

骨质疏松性髋部骨折需要特定的治疗方法,因为老年患者术后出现不良后果的风险很高。特别是,谵妄常在围手术期发生,且与死亡、医院获得性并发症、持续性认知障碍、术后功能恢复不佳以及医疗费用增加有关。术前对谵妄风险因素进行评估可改进预防措施。谵妄诊断工具应纳入髋部骨折老年骨科治疗标准。鉴于临床表现日益复杂,我们对髋部骨折患者谵妄的现有治疗选择进行综述。术前代谢紊乱和合并疾病的管理是治疗的特定目标,以优化术后结果。特别是,患有阿尔茨海默病的老年患者极易发生髋部骨折和谵妄,且身体极度虚弱,生理储备减少。将环境和药物策略相结合的综合方法对谵妄治疗有用,骨科和老年医学团队之间需密切协作。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验