Ozcimen Muammer, Sakarya Yasar, Kurtipek Ercan, Bekci Taha T, Goktas Sertan, Sakarya Rabia, Yener Halil I, Demir Lutfi S, Erdogan Erkan, Ivacik Ismail S, Alpfidan Ismail, Bukus Abdulkadir
a Department of Ophthalmology and.
b Department of Chest Medicine , Konya Training and Research Hospital , Konya , Turkey .
Cutan Ocul Toxicol. 2016 Mar;35(1):26-30. doi: 10.3109/15569527.2015.1004079. Epub 2015 Feb 18.
To evaluate the peripapillary choroidal thickness of patients with chronic obstructive pulmonary disease (COPD) via enhanced depth imaging optical coherence tomography (EDI-OCT).
A total of 80 patients with COPD (80 eyes) and 50 control subjects (50 eyes) were enrolled. Choroidal scans and the retinal nerve fiber layer (RNFL) thickness were obtained for all eyes using OCT.
The average peripapillary choroidal thickness measurements of the COPD group (147.58 ± 53.53 μm) were lower than the control group (160.84 ± 44.73 μm) (p = 0.068). Inferior segment thicknesses were significantly thinner than the other segments (p < 0.05). Subfoveal choroidal thickness and RNFL thickness measurements of the COPD group were also lower than those of the control group (p = 0.111).
Hypoxia in COPD seems to affect the choroidal thickness. Thinning of the choroid may be attributed to increased vascular resistance and reduced blood flow in patients with COPD. The possible effects of the disease to the eye may be clarified through the role of the choroidal vasculature in the blood supply of the anterior optic nerve head.
通过增强深度成像光学相干断层扫描（EDI-OCT）评估慢性阻塞性肺疾病（COPD）患者的视乳头周围脉络膜厚度。
共纳入80例COPD患者（80只眼）和50例对照者（50只眼）。使用OCT对所有眼睛进行脉络膜扫描并测量视网膜神经纤维层（RNFL）厚度。
COPD组视乳头周围脉络膜平均厚度测量值（147.58±53.53μm）低于对照组（160.84±44.73μm）（p = 0.068）。下方节段厚度显著薄于其他节段（p < 0.05）。COPD组黄斑中心凹下脉络膜厚度和RNFL厚度测量值也低于对照组（p = 0.111）。
COPD中的缺氧似乎会影响脉络膜厚度。脉络膜变薄可能归因于COPD患者血管阻力增加和血流减少。通过脉络膜血管系统在视神经乳头前部血液供应中的作用，可能会阐明该疾病对眼睛的潜在影响。
