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[人乳头瘤病毒疫苗接种前时代西班牙大学生对该疫苗的接受度:一项横断面研究]

[Acceptability of the HPV vaccine among Spanish university students in the pre-vaccine era: a cross-sectional study].

作者信息

Caballero-Pérez Pablo, Tuells José, Rementería Joseba, Nolasco Andreu, Navarro-López Vicente, Arístegui Javier

机构信息

José Tuells, Cátedra de Vacunología "Balmis" UA-FISABIO. Universidad de Alicante, Ctra. de San Vicente del Raspeig s/n. 03690 Alicante, Spain.

出版信息

Rev Esp Quimioter. 2015 Feb;28(1):21-8.

Abstract

INTRODUCTION

Cervical cancer (CC), the second most common cause of cancer deaths in women, is associated with the infection of human papillomavirus (HPV) and is more prevalent in women between the ages of 20 and 24. This research is aimed to determine the background about CC, the human papillomavirus infection and its vaccine, assessing its acceptability in university students.

METHODS

Cross-sectional study over 1,750 students from the University of Alicante (2008) selected at random, proportional associated to gender and studies, by a validated ad-hoc questionnaire. Percentages were computed, confidence intervals, contingency tables according to sex, age and type of studies, calculating adjusted odd ratios (OR).

RESULTS

A sample with 58.6 % of women and 6.6% of biohealth students was obtained. 87.3% were willing to have the vaccine to prevent human papillomavirus (HPV), 94.3% would give this vaccine to their daughters, and 48.0% had heard someone talk about the vaccine. 90.6% didn't have a lot of knowledge about the HPV infection and 82.2% didn't know much about the vaccine. 22.4% had knowledge of the association between HPV and CC. Women register higher OR in acknowledging the problem and are more receptive to having the vaccine. The HPV vaccine acceptability is associated to the sex, the confidence of vaccines as a preventive method; the influence of the background is low in relation to the vaccine predisposition.

CONCLUSIONS

A high acceptability of the vaccine was observed in the period of the study. Raising confidence in people about the vaccines can influence for a better predisposition to be vaccinated.

摘要

引言

宫颈癌(CC)是女性癌症死亡的第二大常见原因,与人乳头瘤病毒(HPV)感染有关,在20至24岁的女性中更为普遍。本研究旨在确定宫颈癌、人乳头瘤病毒感染及其疫苗的背景情况,评估其在大学生中的可接受性。

方法

通过一份经过验证的专门问卷,对阿利坎特大学1750名学生(2008年)进行横断面研究,随机选取,按性别和专业成比例抽取。计算百分比、置信区间,根据性别、年龄和专业类型编制列联表,计算调整后的比值比(OR)。

结果

获得了一个样本,其中女性占58.6%,生物健康专业学生占6.6%。87.3%的人愿意接种预防人乳头瘤病毒(HPV)的疫苗,94.3%的人会给女儿接种这种疫苗,48.0%的人听说过有人谈论这种疫苗。90.6%的人对HPV感染了解不多,82.2%的人对该疫苗了解不多。22.4%的人知道HPV与宫颈癌之间的关联。女性在认识到这个问题上的OR值更高,并且对接种疫苗更易接受。HPV疫苗的可接受性与性别、对疫苗作为预防方法的信心有关;背景因素对疫苗易感性的影响较小。

结论

在研究期间观察到该疫苗具有较高的可接受性。增强人们对疫苗的信心可以影响其更愿意接种疫苗。

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