Cosic I, Vojisavljevic V, Pavlovic M
Laboratory for Multidisciplinary Research, Boris Kidric Institute-Vinca, Beograd, Yugoslavia.
Int J Radiat Biol. 1989 Aug;56(2):179-91. doi: 10.1080/09553008914551331.
The resonant recognition model (RRM) is a model of protein-protein and protein-DNA interaction based on a significant correlation between spectra of numerical presentation of the amino acid or nucleotide sequences and their biological activity. Having compared absorption characteristics of photosensitive proteins with their RRM spectral characteristics we obtained a linear correlation between the RRM frequency space and real frequency space, which determines a scaling factor between these two frequency spaces. On applying the RRM model to several groups of peptide growth factors, characteristic RRM frequencies were revealed and the corresponding real characteristic frequencies for these groups of growth factors were calculated using the scaling factor previously obtained. The real frequency characteristics of growth factors obtained in this way correspond with maxima in the action spectra of low-intensity light irradiation effects on cell proliferation.
共振识别模型（RRM）是一种基于氨基酸或核苷酸序列的数字表示光谱与其生物活性之间的显著相关性的蛋白质-蛋白质和蛋白质-DNA相互作用模型。通过比较光敏蛋白的吸收特性与其RRM光谱特性，我们获得了RRM频率空间与实际频率空间之间的线性相关性，这确定了这两个频率空间之间的缩放因子。将RRM模型应用于几组肽生长因子时，揭示了特征性的RRM频率，并使用先前获得的缩放因子计算了这些生长因子组对应的实际特征频率。以这种方式获得的生长因子的实际频率特性与低强度光照射对细胞增殖的作用光谱中的最大值相对应。
