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Preliminary expansion of the resonant recognition model to incorporate multi variable analysis.

作者信息

Birch S, West R, Cosic I

机构信息

Department of Electrical and Computer Systems Engineering, Monash University, Caulfield, Victoria.

出版信息

Australas Phys Eng Sci Med. 1995 Dec;18(4):197-207.

PMID:8867390
Abstract

The Resonant Recognition Model (rrm) uses digital signal processing methods to investigate protein structure-function; and links the biological function of protein families to unique characteristic frequencies. The rrm originally used a single set of variables: the electron ion interaction potential (EIIP). Here the rrm has been expanded to include 242 sets of variables to analyse a sample of protein families. Despite the evident increase in complexity of the data, distinguishing patterns can be observed between the different protein families. The thus-obtained Signature Profiles (SP) indicate that proteins having similar overall functions may be identifiable and differentiated from others by their characteristic frequency signatures far more readily than with the single variable rrm spectra.

摘要

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