Bates C J, Powers H J, Thurnham D I
Medical Research Council Dunn Nutrition Unit, Cambridge.
Lancet. 1989 Aug 5;2(8658):313-4. doi: 10.1016/s0140-6736(89)90495-9.
Combined marginal deficiencies of iron, vitamin C, and B-group vitamins are widespread in developing countries. An understanding of the functional implications poses a continuing challenge, both for the development of new techniques of investigation and for the design of effective intervention programmes. Practical intervention in developing countries also needs to take account of the interactions of micronutrient status and disease susceptibility. It is becoming clear that combined deficiencies of certain vitamins, or of iron and vitamins, although less severe than those causing the lesions of classic clinical deficiency, can seriously reduce work performance. Riboflavin, particularly, has a special relation with iron economy.
在发展中国家，铁、维生素C和B族维生素的联合边缘性缺乏情况普遍存在。了解其功能影响对新技术研究的开展以及有效干预计划的设计都构成了持续的挑战。在发展中国家进行实际干预时，还需要考虑微量营养素状况与疾病易感性之间的相互作用。越来越明显的是，某些维生素的联合缺乏，或者铁与维生素的联合缺乏，尽管不如那些导致典型临床缺乏症病变的情况严重，但会严重降低工作能力。特别是核黄素，与铁的代谢有着特殊关系。
