Amiraraghi N, Robertson S, Iyer A
Department of Otolaryngology,Head and Neck Surgery,NHS Lanarkshire,Airdrie,Lanarkshire,UK.
Department of Otolaryngology,Head and Neck Surgery,NHS Greater Glasgow,Scotland,UK.
J Laryngol Otol. 2015 Feb;129(2):179-82. doi: 10.1017/S0022215114002527.
A primary otological presentation of granulomatosis with polyangiitis is rare. We present four cases of granulomatosis with polyangiitis with different otological manifestations.
A literature review of granulomatosis with polyangiitis cases presenting to otolaryngologists was undertaken. A case series review of four patients presenting within a 12-month period was also performed. One patient had serous otitis media which worsened after myringotomy. Two patients presented with acute ear infection and facial palsy and one with acute mastoiditis. All were positive for antineutrophilic cytoplasmic antibody, and three had positive findings upon histological analysis.
When acute supposed ear infections fail to respond to treatment (antibiotics or surgery), rarer causes of the symptoms should be considered. By reporting this case series, we aim to improve the early diagnosis of granulomatosis with polyangiitis to enable timely treatment and prevent systemic involvement.
Zotero 插件