（N末端脑钠肽前体）BNP在充血性心力衰竭诊断、预后及治疗中的价值
The value of (NT-pro) BNP in the diagnosis, prognosis and treatment of congestive heart failure.
作者信息
van Kimmenade R R J, Bakker J A, Crijns H J G M, van Dieijen-Visser M P, Pinto Y M
出版信息
Neth Heart J. 2004 Feb;12(2):61-63.
Abstract
Congestive heart failure constitutes one of the major causes of morbidity and mortality in Western countries. However, it is often misdiagnosed and the validity of the diagnosis is often difficult to establish. The clinical signs are not very sensitive and symptoms are nonspecific. Secretion of natriuretic peptides is increased in situations of cardiac overload. Testing the levels of these peptides, especially BNP and NT-proBNP, appears to offer a significant advance in the diagnosis and treatment of heart failure. In this article we would like to discuss the value of natriuretic peptides in congestive heart failure and give a short review of the literature.
摘要
充血性心力衰竭是西方国家发病和死亡的主要原因之一。然而，它常常被误诊，且诊断的准确性往往难以确定。临床体征不太敏感，症状也不具有特异性。在心脏负荷过重的情况下，利钠肽的分泌会增加。检测这些肽的水平，尤其是脑钠肽（BNP）和N末端脑钠肽原（NT-proBNP），似乎在心力衰竭的诊断和治疗方面取得了重大进展。在本文中，我们将讨论利钠肽在充血性心力衰竭中的价值，并对相关文献进行简要综述。
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本文引用的文献
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B-type natriuretic peptide predicts future cardiac events in patients presenting to the emergency department with dyspnea.B型利钠肽可预测因呼吸困难到急诊科就诊患者未来发生心脏事件的风险。
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Role of brain natriuretic peptide in risk stratification of patients with congestive heart failure.脑钠肽在充血性心力衰竭患者危险分层中的作用。
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Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide (N-BNP) concentrations.以血浆氨基末端脑钠肽（N-BNP）浓度为指导的心力衰竭治疗。
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