van Kimmenade R R J, Bakker J A, Crijns H J G M, van Dieijen-Visser M P, Pinto Y M
Neth Heart J. 2004 Feb;12(2):61-63.
Congestive heart failure constitutes one of the major causes of morbidity and mortality in Western countries. However, it is often misdiagnosed and the validity of the diagnosis is often difficult to establish. The clinical signs are not very sensitive and symptoms are nonspecific. Secretion of natriuretic peptides is increased in situations of cardiac overload. Testing the levels of these peptides, especially BNP and NT-proBNP, appears to offer a significant advance in the diagnosis and treatment of heart failure. In this article we would like to discuss the value of natriuretic peptides in congestive heart failure and give a short review of the literature.
充血性心力衰竭是西方国家发病和死亡的主要原因之一。然而，它常常被误诊，且诊断的准确性往往难以确定。临床体征不太敏感，症状也不具有特异性。在心脏负荷过重的情况下，利钠肽的分泌会增加。检测这些肽的水平，尤其是脑钠肽（BNP）和N末端脑钠肽原（NT-proBNP），似乎在心力衰竭的诊断和治疗方面取得了重大进展。在本文中，我们将讨论利钠肽在充血性心力衰竭中的价值，并对相关文献进行简要综述。
