Rujic Dragana, Pareek Manan, Egholm Gro, Thygesen Kristian
Medicinsk Forskningsafdeling, Odense Universitetshospital, Svendborg Sygehus, Valdemarsgade 53, 5700 Svendborg.
Ugeskr Laeger. 2015 Feb 9;177(7).
The essential role of cardiac troponin (cTn) in the diagnosis of acute myocardial infarction has led to the development of high-sensitivity assays, which are able to detect very small amounts of myocardial necrosis. However, although elevated blood levels of cTn indicate myocardial injury, they do not provide a causal explanation. The differential diagnosis of minor elevations of the cTn-level is broad and includes both acute and chronic cardiac and non-cardiac conditions. The purpose of this paper is to review common causes of elevated cTn-levels in daily clinical practice.
心肌肌钙蛋白(cTn)在急性心肌梗死诊断中的重要作用促使了高灵敏度检测方法的发展,这些方法能够检测到极少量的心肌坏死。然而,尽管血液中cTn水平升高表明心肌损伤,但它们并不能提供因果解释。cTn水平轻度升高的鉴别诊断范围广泛,包括急性和慢性心脏及非心脏疾病。本文的目的是回顾日常临床实践中cTn水平升高的常见原因。