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[儿童肠衰竭管理的进展]

[Advances in the management of children with intestinal failure].

作者信息

Alberti R Gigliola, Le Roy O Catalina, Cofré D Colomba, Pattillo S Juan Carlos, Domínguez B Pilar, Guerra C Juan Francisco

出版信息

Rev Chil Pediatr. 2014 Apr;85(2):148-56. doi: 10.4067/S0370-41062014000200003.

Abstract

Intestinal failure is defined as the reduction of a functional gut mass below the minimal necessary for adequate digestion and absorption of nutrients and fluids. Intestinal failure is the final result of a number of different causes, being short bowel syndrome the most recognized. Its prevalence is low, but the impact in quality of life among patients and their families is critical. Furthermore, is associated with high economic costs, both for the patient and the health provider. Its main feature is the need for long-term parenteral nutritional support with high morbidity and mortality associated complications, such as line-derived bloodstream infections and liver disease. The management of these patients should be performed by a multidisciplinary team, and be aimed at promoting adaptation and recovery of bowel function to achieve intestinal autonomy.

摘要

肠衰竭的定义为功能性肠管量减少至低于充分消化和吸收营养物质及液体所需的最低限度。肠衰竭是多种不同病因的最终结果,其中短肠综合征最为人熟知。其患病率较低,但对患者及其家庭生活质量的影响至关重要。此外,它还会给患者和医疗服务提供者带来高昂的经济成本。其主要特征是需要长期肠外营养支持,且伴有诸如导管相关血流感染和肝病等高发病率和死亡率的并发症。这些患者的管理应由多学科团队进行,目标是促进肠道功能的适应和恢复以实现肠道自主。

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