DraI and PstI RFLPs in the tyrosine hydroxylase (TH) and insulin gene (INS) region of chromosome 11.
作者信息
Sten-Linder M, Granqvist M, Stern I, Bell G I, Luthman H
机构信息
Department of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden.
出版信息
Nucleic Acids Res. 1989 Jul 25;17(14):5873. doi: 10.1093/nar/17.14.5873.
Abstract
摘要
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DraI and PstI RFLPs in the tyrosine hydroxylase (TH) and insulin gene (INS) region of chromosome 11.11号染色体酪氨酸羟化酶（TH）和胰岛素基因（INS）区域的DraI和PstI限制性片段长度多态性
Nucleic Acids Res. 1989 Jul 25;17(14):5873. doi: 10.1093/nar/17.14.5873.
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Human tyrosine hydroxylase (TH) genomic fragment (pHGTH4) identifies a PstI polymorphism.人酪氨酸羟化酶（TH）基因组片段（pHGTH4）可识别一种PstI多态性。
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Human tyrosine hydroxylase and insulin genes are contiguous on chromosome 11.人类酪氨酸羟化酶基因和胰岛素基因在11号染色体上相邻。
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Polymorphism of the insulin gene is associated with increased prostate cancer risk.胰岛素基因多态性与前列腺癌风险增加有关。
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Tyrosine hydroxylase maps to the short arm of chromosome 11 proximal to the insulin and HRAS1 loci.酪氨酸羟化酶定位于11号染色体短臂，靠近胰岛素和HRAS1基因座。
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A new highly polymorphic DNA restriction site marker in the 5' region of the human tyrosine hydroxylase gene (TH) detecting loss of heterozygosity in human embryonal rhabdomyosarcoma.人类酪氨酸羟化酶基因（TH）5'区域中的一种新的高度多态性DNA限制性酶切位点标记，可检测人类胚胎性横纹肌肉瘤中的杂合性缺失。
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引用本文的文献
1
DNA polymorphisms in the human tyrosine hydroxylase/insulin/insulin-like growth factor II chromosomal region in relation to glucose and insulin responses.人类酪氨酸羟化酶/胰岛素/胰岛素样生长因子II染色体区域的DNA多态性与葡萄糖及胰岛素反应的关系
Diabetologia. 1993 Jan;36(1):25-32. doi: 10.1007/BF00399089.
本文引用的文献
1
Polymorphic DNA region adjacent to the 5' end of the human insulin gene.人类胰岛素基因5'端相邻的多态性DNA区域。
Proc Natl Acad Sci U S A. 1981 Sep;78(9):5759-63. doi: 10.1073/pnas.78.9.5759.
2
Human tyrosine hydroxylase (TH) genomic fragment (pHGTH4) identifies a PstI polymorphism.人酪氨酸羟化酶（TH）基因组片段（pHGTH4）可识别一种PstI多态性。
Nucleic Acids Res. 1988 Aug 11;16(15):7760. doi: 10.1093/nar/16.15.7760.
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