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经尿道等离子纽扣状汽化术治疗前列腺癌根治术后复发性膀胱尿道吻合口狭窄

Treatment of recurrent vesicourethral anastomotic stricture after radical prostatectomy using plasma-button vaporization.

作者信息

Öztürk Hakan

机构信息

a Department of Urology, School of Medicine, Sifa University , Izmir, Turkey.

出版信息

Scand J Urol. 2015;49(5):371-6. doi: 10.3109/21681805.2015.1012115. Epub 2015 Feb 19.

Abstract

OBJECTIVE

The aim of this study was to evaluate the efficiency of plasma-button vaporization (PBV) in the treatment of recurrent vesicourethral anastomotic stricture (VUAS) following retropubic radical prostatectomy (RRP).

MATERIALS AND METHODS

A total of 28 patients (28/138, 20.2%) who had been diagnosed with recurrent VUAS after undergoing RRP to treat localized prostate cancer between January 2008 and January 2014 were treated using PBV. The anastomosis site was vaporized from all quadrants using a PBV electrode. The preoperative and postoperative serum prostate-specific antigen, prostate size, body mass index, pathological tumour stage and previous transurethral resection of the prostate were recorded.

RESULTS

All patients had localized prostate cancer (stage ≤ PT3a), and all RRP operations were performed by the same surgeon in a single centre. The mean age was 65.2 ± 7.34 years (range 51-73 years). All patients had undergone previous attempts to open the bladder neck: 21 patients (75%) by dilatation and seven (25%) by internal urethrotomy. The procedure was performed once in 23 patients and twice in five patients. After a mean follow-up of 24 months (range 6-66 months), 25 patients (89.2%) had a well-healed and widely patent bladder neck.

CONCLUSIONS

The PBV technique proved to be efficient and successful in the treatment of recurrent anastomotic stenosis developing after RRP in terms of both short- and long-term outcomes. The removal of fibrotic tissue with vaporization and avoiding cauterization due to minimal haemorrhage were considered advantageous with regard to recurrence.

摘要

目的

本研究旨在评估等离子体纽扣汽化术(PBV)治疗耻骨后根治性前列腺切除术(RRP)后复发性膀胱尿道吻合口狭窄(VUAS)的疗效。

材料与方法

2008年1月至2014年1月期间,共有28例(28/138,20.2%)因局限性前列腺癌接受RRP治疗后被诊断为复发性VUAS的患者接受了PBV治疗。使用PBV电极从各个象限汽化吻合部位。记录术前和术后血清前列腺特异性抗原、前列腺大小、体重指数、病理肿瘤分期以及既往经尿道前列腺切除术情况。

结果

所有患者均为局限性前列腺癌(分期≤PT3a),所有RRP手术均由同一外科医生在单一中心完成。平均年龄为65.2±7.34岁(范围51 - 73岁)。所有患者此前均曾尝试打开膀胱颈:21例(75%)采用扩张术,7例(25%)采用尿道内切开术。23例患者手术进行了1次,5例患者进行了2次。平均随访24个月(范围6 - 66个月)后,25例患者(89.2%)膀胱颈愈合良好且通畅。

结论

就短期和长期结果而言,PBV技术在治疗RRP后发生的复发性吻合口狭窄方面被证明是有效且成功的。汽化去除纤维化组织以及因出血极少而避免烧灼被认为对预防复发有利。

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