Gupta A, Vernon S A
Ophthalmology Department, Queen's Medical Centre, Nottingham, UK.
Eye (Lond). 2015 Oct;29(10):1299-307. doi: 10.1038/eye.2014.331. Epub 2015 Feb 20.
To determine whether the 1-day postoperative intraocular pressure (IOP) check following routine uncomplicated phacoemulsification is necessary in patients with pre-existing glaucoma and ocular hypertension (OHT), if acetazolamide prophylaxis is used. To investigate the practice of U.K. glaucoma specialists in IOP rise prophylaxis and follow-up regimes.
The IOP 1-day postoperatively was analysed against the last recorded IOP before phacoemulsification in a cohort of patients with glaucoma or OHT who underwent uncomplicated phacoemulsification cataract surgery between December 2009 and September 2012, where it was routine practice to give acetazolamide postoperatively. U.K. and Eire Glaucoma Society members were surveyed via an online questionnaire to analyse practice among U.K. glaucoma specialists.
One hundred and seven eyes were studied: 99 with glaucoma and 8 with OHT. The mean IOP change was -0.8 mm Hg with only two eyes measuring >30 mm Hg postoperatively (2%). Both these eyes received 750 mg acetazolamide. Eighteen (17%) eyes had an IOP rise of at least 30%. In the survey of practice there were 65 respondents. Twenty-one (32%) respondents did not use IOP prophylaxis. Only 17 (26%) of respondents routinely reviewed their patients 1-day postoperatively.
Our prophylactic acetazolamide regime does not completely eliminate the risk of an IOP >30 mm Hg on day 1 post routine phacoemulsification in glaucoma/OHT patients. Patients with pre-existing glaucoma, despite acetazolamide prophylaxis, will require IOP management decisions on the first postoperative day after uncomplicated phacoemulsification surgery. U.K. expert practice is non-uniform with regard to IOP prophylaxis, and the 1-day review, and further discussion and formulation of consensus appears necessary.
确定对于术前已患有青光眼和高眼压症(OHT)的患者,在使用乙酰唑胺进行预防的情况下,常规非复杂性白内障超声乳化术后1天进行眼压(IOP)检查是否必要。调查英国青光眼专家在预防眼压升高及随访方案方面的做法。
对2009年12月至2012年9月期间接受非复杂性白内障超声乳化手术的青光眼或高眼压症患者队列,分析其术后1天的眼压,并与白内障超声乳化术前最后记录的眼压进行对比,这些患者术后常规使用乙酰唑胺。通过在线问卷对英国和爱尔兰青光眼协会成员进行调查,以分析英国青光眼专家的做法。
共研究了107只眼:99只患有青光眼,8只患有高眼压症。平均眼压变化为-0.8 mmHg,术后仅有2只眼眼压测量值>30 mmHg(2%)。这两只眼均接受了750 mg乙酰唑胺治疗。18只(17%)眼眼压升高至少30%。在做法调查中有65名受访者。21名(32%)受访者未使用眼压预防措施。只有17名(26%)受访者常规在术后1天对患者进行复查。
我们的乙酰唑胺预防方案并不能完全消除青光眼/OHT患者在常规白内障超声乳化术后第1天眼压>30 mmHg的风险。对于术前已患有青光眼的患者,尽管使用了乙酰唑胺预防,在非复杂性白内障超声乳化手术后的第一天仍需要进行眼压管理决策。英国专家在眼压预防和术后1天复查方面的做法并不统一,似乎有必要进行进一步讨论并形成共识。