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[健康人排矿肾功能的昼夜节律及其在缺血性心脏病中的变化]

[Circadian rhythms of mineral-excreting kidney function in healthy persons and their changes in ischemic heart disease].

作者信息

Aslanian N L, Babaian L A, Asatrian M A, Krishchian E M, Gabrielian R S

出版信息

Ter Arkh. 1989;61(4):45-8.

PMID:2569774
Abstract

Seventy normal persons and 100 patients with coronary disease were examined for circadian rhythms of urine and minerals excretion. The data obtained demonstrate that normal persons were characterized by circadian rhythms of urine and minerals excretion with a definite confidence interval of mesor and amplitude fluctuations. Angina pectoris of effort was marked by infradian rhythms of mineral excreting renal function. Monotherapy with beta-blockers or calcium antagonists given in courses entailed the recovery of the circadian rhythms of mineral-excreting renal function. Parameters of the rhythms of urine and minerals excretion in patients with angina pectoris of effort and rest noticeably differed from those in patients with angina pectoris of effort. In 30.7 percent of the persons, the use of the mathematic methods did not reveal any significant rhythms. The circadian range was found to predominate among the significant rhythms. Antianginal treatment did not produce any appreciable changes.

摘要

对70名正常人及100名冠心病患者进行了尿和矿物质排泄昼夜节律的检查。所获数据表明,正常人具有尿和矿物质排泄的昼夜节律,其平均周相和振幅波动有一定的可信区间。劳力型心绞痛的特点是矿物质排泄肾功能的亚日节律。长期给予β受体阻滞剂或钙拮抗剂单一疗法可使矿物质排泄肾功能的昼夜节律恢复。劳力型心绞痛患者与静息型心绞痛患者的尿和矿物质排泄节律参数明显不同。在30.7%的人当中,运用数学方法未发现任何显著节律。在显著节律中,昼夜范围占主导。抗心绞痛治疗未产生任何明显变化。

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