[酮替芬制剂对β受体阻滞剂的可能影响]
[The possible effect of a ketotifen preparation on beta-receptor blockade].
作者信息
Kosturkov G, Markov M, Vŭlcheva T, Popov T
出版信息
Vutr Boles. 1989;28(2):19-22.
PMID:2569788
Abstract
Parallel clinico-pharmacological studies were carried out of ketotifen action in patients with atopic bronchial asthma and in an experimental model of beta-adrenergic blockade in guinea pigs. The results revealed that ketotifen acts on the beta-adrenergic blockade in the patients with atopic bronchial asthma and in the experimental model in guinea pigs. The ketotifen action on beta-adrenergic blockade resembles that of glucocorticosteroids in efficiency.
摘要
对特应性支气管哮喘患者以及豚鼠β-肾上腺素能阻断实验模型进行了酮替芬作用的平行临床药理学研究。结果显示，酮替芬对特应性支气管哮喘患者以及豚鼠实验模型中的β-肾上腺素能阻断均有作用。酮替芬对β-肾上腺素能阻断的作用在效果上类似于糖皮质激素。
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