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经皮腔内球囊血管成形术治疗自体血液透析动静脉内瘘狭窄:技术成功率及影响术后内瘘通畅因素分析

Percutaneous transluminal balloon angioplasty in stenosis of native hemodialysis arteriovenous fistulas: technical success and analysis of factors affecting postprocedural fistula patency.

作者信息

Aktas Ayse, Bozkurt Alper, Aktas Bulent, Kirbas Ismail

机构信息

Department of Radiology, Turgut Özal University School of Medicine, Ankara, Turkey.

出版信息

Diagn Interv Radiol. 2015 Mar-Apr;21(2):160-6. doi: 10.5152/dir.2014.14348.

Abstract

PURPOSE

We aimed to determine the predictors of technical success and patency after percutaneous transluminal angioplasty (PTA) of de novo dysfunctional hemodialysis arteriovenous fistulas (AVF).

METHODS

We performed a retrospective analysis of first time PTA in 228 patients (129 men, 99 women; mean age, 56.8±14.6 years). Anatomical (location, length, grade, and number of stenoses) and clinical variables (sex, age, prior AVF, diabetes mellitus, AVF age, side, and location) were reviewed.

RESULTS

A total of 330 stenoses were found in 228 patients. PTA was technically successful in 96.3% of the stenoses (n=319). Clinical success was achieved in 97.2% (n=321). Early dysfunction (within six months) was positively correlated with patient age (P < 0.001) and diabetes (P < 0.005). Older age (P < 0.001) and diabetes (P = 0.002) were associated with a lower primary patency rate. Patient age (P %lt; 0.001), presence of diabetes (P = 0.023), length of stenosis (P = 0.003), early recurrence (P = 0.003) and presence of residual stenosis (P = 0.014) were associated with a lower secondary patency rate.

CONCLUSION

Patency of dysfunctional hemodialysis fistulas can be maintained safely with continuous follow-up and repeated interventions without shortening the venous segment by surgical revision. Percutaneous approach to hemodialysis access stenosis is an alternative to the conventional surgical approach and PTA is an effective treatment method for dysfunctional AVF.

摘要

目的

我们旨在确定初次功能障碍性血液透析动静脉内瘘(AVF)经皮腔内血管成形术(PTA)后技术成功和通畅的预测因素。

方法

我们对228例患者(129例男性,99例女性;平均年龄56.8±14.6岁)的首次PTA进行了回顾性分析。回顾了解剖学(狭窄部位、长度、分级和数量)和临床变量(性别、年龄、既往AVF、糖尿病、AVF使用时间、侧别和部位)。

结果

228例患者共发现330处狭窄。PTA在96.3%的狭窄处(n = 319)技术成功。临床成功率为97.2%(n = 321)。早期功能障碍(6个月内)与患者年龄(P < 0.001)和糖尿病(P < 0.005)呈正相关。年龄较大(P < 0.001)和糖尿病(P = 0.002)与较低的初次通畅率相关。患者年龄(P < 0.001)、糖尿病的存在(P = 0.023)、狭窄长度(P = 0.003)、早期复发(P = 0.003)和残余狭窄的存在(P = 0.014)与较低的二次通畅率相关。

结论

通过持续随访和重复干预可以安全维持功能障碍性血液透析内瘘的通畅,而无需通过手术修复缩短静脉段。经皮处理血液透析通路狭窄是传统手术方法的一种替代方法,PTA是治疗功能障碍性AVF的有效治疗方法。

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