Es-Sbissi F, Nitassi S, Boulaadas M, Essakalli L
Service ORL et chirurgie cervico-faciale, Hôpital des Spécialités, CHU Rabat, Université Mohammed V, Avenue Abderrahim Bouabid, Rabat, Morocco.
Service ORL et chirurgie cervico-faciale, Hôpital des Spécialités, CHU Rabat, Université Mohammed V, Avenue Abderrahim Bouabid, Rabat, Morocco.
Eur Ann Otorhinolaryngol Head Neck Dis. 2015 Jun;132(3):161-3. doi: 10.1016/j.anorl.2015.01.006. Epub 2015 Feb 16.
Angiosarcoma is a malignant tumour arising from endothelial cells that accounts for 1% of all sarcomas. The sinonasal site of angiosarcoma is exceptional.
The authors report a case of sinonasal angiosarcoma in a 53-year-old man. Despite wide resection by open surgery and postoperative chemoradiotherapy, several tumour recurrences were observed, requiring multiple operations.
Only histological examination with immunohistochemistry is able to confirm the diagnosis (factor VIII, CD34 and CD31 antigens). Standard treatment consists of surgery with wide resection followed by radiotherapy. The authors discuss the treatment modalities and prognosis of this tumour.
血管肉瘤是一种起源于内皮细胞的恶性肿瘤，占所有肉瘤的1%。血管肉瘤发生于鼻窦部位的情况较为罕见。
作者报告了一例53岁男性鼻窦血管肉瘤病例。尽管通过开放手术进行了广泛切除并术后进行了放化疗，但仍观察到多次肿瘤复发，需要进行多次手术。
只有通过免疫组织化学的组织学检查才能确诊（VIII因子、CD34和CD31抗原）。标准治疗包括广泛切除手术，随后进行放疗。作者讨论了该肿瘤的治疗方式和预后。
