Sun Bo, Ito Toshiro
Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore Singapore.
Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore Singapore ; Department of Biological Sciences, National University of Singapore Singapore.
Front Plant Sci. 2015 Feb 2;6:17. doi: 10.3389/fpls.2015.00017. eCollection 2015.
In Arabidopsis, floral stem cells are maintained only at the initial stages of flower development, and they are terminated at a specific time to ensure proper development of the reproductive organs. Floral stem cell termination is a dynamic and multi-step process involving many transcription factors, chromatin remodeling factors and signaling pathways. In this review, we discuss the mechanisms involved in floral stem cell maintenance and termination, highlighting the interplay between transcriptional regulation and epigenetic machinery in the control of specific floral developmental genes. In addition, we discuss additional factors involved in floral stem cell regulation, with the goal of untangling the complexity of the floral stem cell regulatory network.
在拟南芥中,花干细胞仅在花发育的初始阶段得以维持,并且它们会在特定时间终止,以确保生殖器官的正常发育。花干细胞的终止是一个动态的多步骤过程,涉及许多转录因子、染色质重塑因子和信号通路。在本综述中,我们讨论了花干细胞维持和终止所涉及的机制,强调了转录调控和表观遗传机制在控制特定花发育基因方面的相互作用。此外,我们还讨论了参与花干细胞调控的其他因素,目的是理清花干细胞调控网络的复杂性。