Miroslav Vujasinovic, Klemen Mojskerc
Hepatogastroenterology. 2014 Nov-Dec;61(136):2209-11.
BACKGROUND/AIMS: Colonoscopy is associated with pain and discomfort in the majority of patients when performed without sedation. We performed a prospective and randomized study to compare warm water instillation and standard air-insufflation colonoscopy techniques without any sedation.
The data of 122 patients (64 female and 58 male) were statistically analyzed. Patients were randomized into two groups by using computer generated list. In group A, standard colonoscopy with air insufflation was performed. In group B colonoscopy was performed by warm water infusion into the bowel. No analgesic, antispasmodic or sedative medications were used. After colonoscopy, the level of pain during colonoscopy experienced by the patient was measured using the visual analog scale (VAS).
There were no statistically significant differences in gender and average age between the two groups of patients. Cecal intubation was successful in all patients (100%). All colonoscopies were performed without complications. Patients who had colonoscopy with water immersion had a significantly lower level of pain on the VAS (4.09 vs 5.06), p = 0.041.
We confirmed the advantages of warm water instillation for colonoscope insertion in reducing pain without compromising the time to reach the cecum, success of cecum intubation or patient safety.
背景/目的：在未使用镇静剂的情况下进行结肠镜检查时，大多数患者会感到疼痛和不适。我们进行了一项前瞻性随机研究，以比较温水灌注和标准空气注入结肠镜检查技术（均不使用任何镇静剂）。
对122例患者（64例女性，58例男性）的数据进行统计学分析。使用计算机生成的列表将患者随机分为两组。A组进行标准的空气注入结肠镜检查。B组通过向肠内注入温水进行结肠镜检查。未使用止痛、解痉或镇静药物。结肠镜检查后，使用视觉模拟量表（VAS）测量患者在结肠镜检查期间的疼痛程度。
两组患者在性别和平均年龄方面无统计学显著差异。所有患者（100%）的盲肠插管均成功。所有结肠镜检查均无并发症发生。接受水浸式结肠镜检查的患者在VAS上的疼痛程度显著较低（4.09对5.06），p = 0.041。
我们证实了温水灌注在插入结肠镜时在减轻疼痛方面的优势，同时不影响到达盲肠的时间、盲肠插管的成功率或患者安全。
