在择期神经外科手术中，青霉素预防用药5天与1天的比较。

Five days versus one day of penicillin as prophylaxis in elective neurosurgical operations.

作者信息

Cartmill T D, al Zahawi M F, Sisson P R, Ingham H R, Gould F K, Crone P B, Betty M J, Crawford P J, Kalbag R M, Mendelow A D

机构信息

Department of Microbiology, Regional Public Health Laboratory, Newcastle-upon-Tyne, UK.

出版信息

J Hosp Infect. 1989 Jul;14(1):63-8. doi: 10.1016/0195-6701(89)90135-7.

DOI:10.1016/0195-6701(89)90135-7

PMID:2570104

Abstract

Of 423 patients undergoing elective cranial and spinal operations, infections due to Staphylococcus aureus occurred in 3 of 217 (1.4%) receiving penicillin for 1 day, in none of 206 receiving penicillin for 5 days. There was no significant difference in rates of infection between the two groups receiving penicillin. It is concluded that penicillin for 1 day is as effective as penicillin for 5 days, in the prevention of wound infections due to S. aureus.

摘要

在423例接受择期颅脑和脊柱手术的患者中，217例接受1天青霉素治疗的患者中有3例（1.4%）发生了金黄色葡萄球菌感染，206例接受5天青霉素治疗的患者中无1例发生感染。两组接受青霉素治疗的患者感染率无显著差异。得出的结论是，1天的青霉素治疗在预防金黄色葡萄球菌引起的伤口感染方面与5天的青霉素治疗效果相同。