Fulop M
Department of Medicine, Albert Einstein College of Medicine, Bronx, New York.
Lancet. 1989 Sep 2;2(8662):550-1. doi: 10.1016/s0140-6736(89)90664-8.
Enlarged salivary glands are common in patients with hypothyroidism but this finding is not widely appreciated. Although chronic painless enlargement of the salivary glands was reported in papers published 50-60 years ago, mainly in German, it is not mentioned in current textbooks on the thyroid. Along with the parotids, the submandibular and especially the sublingual glands may be quite enlarged, and the enlargement can be a useful clue to the diagnosis of hypothyroidism. The gland enlargement regresses at least partly after thyroid replacement therapy.
甲状腺功能减退患者中唾液腺肿大很常见，但这一发现并未得到广泛认识。尽管50 - 60年前发表的论文（主要用德文）报道了唾液腺的慢性无痛性肿大，但当前关于甲状腺的教科书中并未提及。除腮腺外，颌下腺尤其是舌下腺可能会明显肿大，这种肿大可为甲状腺功能减退的诊断提供有用线索。甲状腺替代治疗后，腺体肿大至少会部分消退。
