Xiao Y, Moghadas S M
Agent-Based Modelling Laboratory,York University,Toronto, Ontario,Canada.
Epidemiol Infect. 2015 Mar;143(4):757-65. doi: 10.1017/S0950268814001447.
In Canada, vaccination policies against the 2009 influenza H1N1 pandemic (H1N1pdm09) were modified at different times during the autumn wave. We hypothesized that ethnicity and place of residence influenced the odds of vaccination. To test this hypothesis, we used vaccination databases for the entire province of Manitoba, and obtained the age distribution of vaccination for First Nations (FN) and non-First Nations (non-FN) populations. We used regression analysis to determine the effect of ethnicity and location of residence on odds of vaccination. We found that individuals with FN identity were over 2.8 times [95% confidence interval (CI) 2.79-2.87] more likely to receive vaccination compared to non-FN individuals. For the FN populations, on-reserve residency was associated with 5.15-fold (95% CI 5.00-5.30) higher odds of vaccination compared to off-reserve residency. Our study highlights the importance of demographic and geographical variables in developing strategies for vaccine prioritization.
在加拿大,针对2009年甲型H1N1流感大流行(H1N1pdm09)的疫苗接种政策在秋季疫情期间的不同时间进行了调整。我们假设种族和居住地点会影响疫苗接种的几率。为了验证这一假设,我们使用了曼尼托巴省全省的疫苗接种数据库,并获取了原住民(FN)和非原住民(非FN)人群的疫苗接种年龄分布。我们使用回归分析来确定种族和居住地点对疫苗接种几率的影响。我们发现,与非FN个体相比,具有FN身份的个体接种疫苗的可能性高出2.8倍以上[95%置信区间(CI)2.79 - 2.87]。对于FN人群,与非保留地居住相比,保留地居住与疫苗接种几率高出5.15倍(95% CI 5.00 - 5.30)相关。我们的研究强调了人口统计学和地理变量在制定疫苗优先分配策略中的重要性。