Buzoianu Eugenia, Moiceanu Mariana, Plesca Doina Anca
Department of Pediatrics, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
"Dr.Victor Gomoiu" Children's Clinical Hospital, Bucharest, Romania.
Maedica (Bucur). 2014 Dec;9(4):338-43.
To assess the correlation between asthma control test and peak expiratory flow measurements in children and the impact of certain factors influencing asthma symptoms perception over their correlation.
A prospective study including 54 patients aged 5 to 18 years old, who have been diagnosed with asthma in "Victor Gomoiu" Children's Clinical Hospital between May 2012-November 2013, was initiated. For each patient a personalized asthma monitoring plan was designed. This presumes many evaluations assigned to assess the asthma control status. These evaluations consist in counting of asthma symptoms using ACT (Asthma Control Test) and evaluation of pulmonary function using PEF measurement (peak expiratory flow) and spirometry. In each patient factors known to have an influence on asthma symptoms perception (small age, overweighting and allergic rhinitis) were searched. Finally, the correlation between ACT value and PEF variation and how this correlation is influenced by these factors were assessed.
From all 54 included patients a total of 113 evaluations moments were recorded. The assessment of correlation between ACT score and PEF variation for all evaluations showed a strong correlation overall (p<0.01). The correlation is stronger in the small age group (5 to 6 years: p<0.01) than in the older age group (6 to 11 years: p=0.014, >12 years: p=0.03). ACT does not correlate with PEF variation in the overweight patients subgroup (p=0.226). We found the percent of overweight equal to 8.57% in the small age subgroup (5 to 6 years), 26.78% in the 6 to 11 years old group and 31.81% in the over 12 years old patient group. ACT is correlated with PEF variation in both the allergic rhinitis and non allergic rhinitis subgroups (p<0.01).
ACT is correlated with PEF variation overall. Their correlation is not influenced by small age and the presence of allergic rhinitis, but is influenced by overweighting.
评估儿童哮喘控制测试与呼气峰值流量测量之间的相关性，以及某些影响哮喘症状感知的因素对它们之间相关性的影响。
开展一项前瞻性研究，纳入2012年5月至2013年11月期间在“维克托·戈莫尤”儿童医院被诊断为哮喘的54例5至18岁患者。为每位患者设计了个性化的哮喘监测计划。这需要进行多次评估以评估哮喘控制状态。这些评估包括使用哮喘控制测试（ACT）计算哮喘症状，以及使用呼气峰值流量（PEF）测量和肺量计评估肺功能。在每位患者中，查找已知对哮喘症状感知有影响的因素（年龄小、超重和变应性鼻炎）。最后，评估ACT值与PEF变化之间的相关性以及这些因素如何影响这种相关性。
在所有纳入的54例患者中，共记录了113个评估时刻。对所有评估的ACT评分与PEF变化之间的相关性评估显示总体相关性很强（p<0.01）。年龄小的组（5至6岁：p<0.01）中的相关性比年龄大的组（6至11岁：p=0.014，>12岁：p=0.03）更强。在超重患者亚组中，ACT与PEF变化不相关（p=0.226）。我们发现年龄小的亚组（5至6岁）中超重百分比为8.57%，6至11岁组为26.78%，12岁以上患者组为31.81%。在变应性鼻炎和非变应性鼻炎亚组中，ACT均与PEF变化相关（p<0.01）。
ACT总体上与PEF变化相关。它们之间的相关性不受年龄小和变应性鼻炎的影响，但受超重的影响。
