Mitra Sayantanava, Haque Nizamie S, Goyal Nishant, Tikka Sai Krishna
Department of Psychiatry, Sarojini Naidu Medical College, Agra, Uttar Pradesh 282002, India.
Department of Psychiatry and K.S. Mani Centre for Cognitive Neurosciences, Central Institute of Psychiatry, Ranchi, Jharkhand 834006, India.
Asian J Psychiatr. 2015 Apr;14:19-21. doi: 10.1016/j.ajp.2015.01.013. Epub 2015 Feb 8.
Mirror neuron system (MNS) has been demonstrated to be defective in patients with schizophrenia. This paper report findings from a high resolution (192-channel) EEG study conducted on 15 drug free/naïve consenting schizophrenia patients, in which the specific role of right hemispheric MNS has been explored over 4 weeks of antipsychotic treatment. The authors used mu wave suppression paradigm, and found that baseline right MNS mu suppression correlated negatively with and predicted relative improvement in thought disturbance cluster score of PANSS during first 4 weeks of drug treatment.
镜像神经元系统（MNS）已被证明在精神分裂症患者中存在缺陷。本文报告了一项对15名未服用药物/初次同意参与研究的精神分裂症患者进行的高分辨率（192通道）脑电图研究的结果，该研究在4周的抗精神病药物治疗过程中探索了右半球MNS的具体作用。作者采用了μ波抑制范式，发现基线时右侧MNS的μ波抑制与药物治疗前4周PANSS思维障碍聚类评分的相对改善呈负相关，并可预测该评分的相对改善。
