Ott Sabine, Struffert Tobias, Saake Marc, Gölitz Philipp, Adamek Edyta, Doerfler Arnd
Department of Neuroradiology, University of Erlangen-Nuremberg, Erlangen, Germany
Department of Neuroradiology, University of Erlangen-Nuremberg, Erlangen, Germany.
Acta Radiol. 2016 Feb;57(2):233-40. doi: 10.1177/0284185115571988. Epub 2015 Feb 22.
C-arm flat panel computed tomography angiography (CA-CTA) is a relatively new imaging modality. Consequently, knowledge about postprocessing parameters and their influence on image quality is still limited, especially for the visualization of implanted microstents.
To optimize reconstruction parameters by evaluating the influence of these different parameters for CA-CTA visualization of microstents in an animal model.
Eleven microstents were implanted within the left common carotid artery of 11 New Zealand white rabbits. Both CA-CTA, using intra-venous delivery of contrast material, and conventional digital subtraction angiography (DSA) was performed. CA-CTA datasets were reconstructed using three different image characteristics (normal, sharp, smooth). Two experienced neuroradiologists evaluated the image quality and performed measurements of inner and outer stent diameters as well as measurements of the lumen area.
Stent deployment was performed successfully in all animals. Inter-observer correlation coefficient for all measurements was high (r = 0.87-0.92). Lumen area and inner stent diameter were significantly smaller in image characteristic "smooth" (P < 0.01) than in "sharp" and "normal". Outer stent diameter was larger in "smooth" than in "sharp" and "normal" (P < 0.01). Stent strut size was significantly wider using image characteristic "smooth". "Sharp" and "normal" compared best to DSA, with "sharp" providing the closest match to DSA measurements, with the trade-off of significantly more noise than in the "normal" reconstructions.
The use of different image characteristics in the postprocessing of CA-CTA datasets has an influence on the visualization of implanted stents. Image characteristic "sharp" and "normal" compared best to DSA.
C型臂平板计算机断层血管造影（CA-CTA）是一种相对较新的成像方式。因此，关于后处理参数及其对图像质量的影响的知识仍然有限，尤其是对于植入的微支架的可视化。
通过评估这些不同参数对动物模型中微支架的CA-CTA可视化的影响来优化重建参数。
在11只新西兰白兔的左颈总动脉内植入11个微支架。使用静脉注射造影剂进行CA-CTA和传统数字减影血管造影（DSA）。使用三种不同的图像特征（正常、锐利、平滑）重建CA-CTA数据集。两名经验丰富的神经放射科医生评估图像质量，并测量支架内径和外径以及管腔面积。
所有动物的支架植入均成功。所有测量的观察者间相关系数都很高（r = 0.87 - 0.92）。图像特征为“平滑”时，管腔面积和支架内径明显小于“锐利”和“正常”时（P < 0.01）。“平滑”时的支架外径大于“锐利”和“正常”时（P < 0.01）。使用图像特征“平滑”时，支架支柱尺寸明显更宽。“锐利”和“正常”与DSA相比最佳，“锐利”与DSA测量值最接近匹配，但与“正常”重建相比，噪声明显更多。
在CA-CTA数据集的后处理中使用不同的图像特征会对植入支架的可视化产生影响。图像特征“锐利”和“正常”与DSA相比最佳。
