Department of Neuroradiology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany.
Eur Radiol. 2011 Aug;21(8):1779-87. doi: 10.1007/s00330-011-2093-7. Epub 2011 Mar 2.
Careful follow up is necessary after intracranial stenting because in-stent restenosis (ISR) or residual stenosis (RS) is not rare. A minimally invasive follow-up imaging technique is desirable. The objective was to compare the visualisation of stents in Flat Detector-CT Angiography (FD-CTA) after intravenous contrast medium injection (i.v.) with Multi Detector Computed Tomography Angiography (MD-CTA) and Digital Subtracted Angiography (DSA) in an animal model.
Stents were implanted in the carotid artery of 12 rabbits. In 6 a residual stenosis (RS) was surgically created. Imaging was performed using FD-CTA, MD-CTA and DSA. Measurements of the inner and outer diameter and cross-section area of the stents were performed. Stenosis grade was calculated.
In subjective evaluation FD-CTA was superior to MD-CTA. FD-CTA was more accurate compared with DSA than MD-CTA. Cross-sectional area of the stent lumen was significantly larger (p < 0.05) in FD-CTA in comparison to MD-CTA. Accurate evaluation of stenosis was impossible in MD-CTA. There was no statistically significant difference in the stenosis grade of DSA and FD-CTA.
Our results show that visualisation of stent and stenosis using intravenous FD-CTA compares favourably with DSA and may replace DSA in the follow-up of patients treated with intracranial stents.
颅内支架置入后需要密切随访，因为支架内再狭窄（ISR）或残余狭窄（RS）并不少见。需要一种微创的随访成像技术。本研究旨在比较静脉注射造影剂后平板探测器 CT 血管造影（FD-CTA）与多探测器 CT 血管造影（MD-CTA）和数字减影血管造影（DSA）在动物模型中对支架显示的效果。
将支架植入 12 只兔颈动脉内，其中 6 只通过手术造成残余狭窄（RS）。使用 FD-CTA、MD-CTA 和 DSA 进行成像。对支架的内、外径和横截面积进行测量。计算狭窄程度。
在主观评估中，FD-CTA 优于 MD-CTA。与 MD-CTA 相比，FD-CTA 与 DSA 相比更准确。与 MD-CTA 相比，FD-CTA 测量的支架管腔横截面积明显更大（p<0.05）。MD-CTA 无法准确评估狭窄程度。DSA 和 FD-CTA 的狭窄程度分级无统计学差异。
我们的结果表明，静脉注射 FD-CTA 显示支架和狭窄的效果优于 DSA，可能替代 DSA 用于颅内支架置入患者的随访。
