Avcu Gülhadiye, Sensoy Gülnar, Çeliksoy Mehmet Halil, Sogut Ayhan, Kefeli Mehmet, Karli Arzu, Belet Nursen
Department of Pediatric Infectious Disease, Ondokuz Mayıs University, Samsun, Turkey.
Pediatr Int. 2015;57(1):155-7. doi: 10.1111/ped.12403.
Leukocytoclastic vasculitis (LCV), a disease characterized by inflammation of the small vessels, presents with palpable purpura, especially in the lower extremities. Its etiology is known to include drugs, infection, collagen tissue disease, and malignancy, but LCV caused by anti-tuberculosis drugs is very rarely seen. This report describes the case of a 12-year-old girl who developed LCV with rifampicin and ethambutol while undergoing anti-tuberculosis treatment due to extensive pulmonary involvement.
白细胞破碎性血管炎(LCV)是一种以小血管炎症为特征的疾病,表现为可触及的紫癜,尤其是在下肢。已知其病因包括药物、感染、胶原组织疾病和恶性肿瘤,但由抗结核药物引起的LCV非常罕见。本报告描述了一名12岁女孩的病例,该女孩在因广泛肺部受累接受抗结核治疗时,使用利福平和乙胺丁醇后发生了LCV。