Apollo Center for Advanced Pediatrics, Indraprastha Apollo Hospital, New Delhi 110076, India.
J Trop Pediatr. 2013 Dec;59(6):507-8. doi: 10.1093/tropej/fmt048. Epub 2013 Jun 18.
Antituberculosis therapy-associated cutaneous leukocytoclastic vasculitis (CLV) has been rarely reported. We describe a case of CLV induced by rifampicin and pyrazinamide. A 14-year-old male diagnosed with disseminated tuberculosis developed purpuric lesions after 1.5 months of treatment. Histopathology was consistent with leukocytoclastic vasculitis. Skin lesion improved after cessation of the two drugs and treatment with corticosteroids.
抗结核治疗相关皮肤白细胞碎裂性血管炎（CLV）很少见。我们描述了一例利福平及吡嗪酰胺引起的 CLV。一名 14 岁男性被诊断为播散性肺结核，在接受治疗 1.5 个月后出现紫癜性皮损。组织病理学符合白细胞碎裂性血管炎。停用这两种药物并使用皮质类固醇治疗后，皮肤病变改善。
