Masillo A, Valmaggia L R, Saba R, Brandizzi M, Lindau J F, Solfanelli A, Curto M, Narilli F, Telesforo L, Kotzalidis G D, Di Pietro D, D'Alema M, Girardi P, Fiori Nastro P
Department of Neurology and Psychiatry, Faculty of Medicine and Odontology, Sapienza University of Rome, Rome, Italy.
Department of Psychology, King's College London, Institute of Psychiatry, Psychology and Neuroscience, Box P077, De Crespigny Park, London, SE5 8AF, UK.
Eur Child Adolesc Psychiatry. 2016 Jan;25(1):7-16. doi: 10.1007/s00787-015-0692-6. Epub 2015 Feb 25.
A personality trait that often elicits poor and uneasy interpersonal relationships is interpersonal sensitivity. The aim of the present study was to explore the relationship between interpersonal sensitivity and psychosocial functioning in individuals at ultra-high risk for psychosis as compared to help-seeking individuals who screened negative for an ultra-high risk of psychosis. A total sample of 147 adolescents and young adult who were help seeking for emerging mental health problems participated in the study. The sample was divided into two groups: 39 individuals who met criteria for an ultra-high-risk mental state (UHR), and 108 (NS). The whole sample completed the Interpersonal Sensitivity Measure (IPSM) and the Global Functioning: Social and Role Scale (GF:SS; GF:RS). Mediation analysis was used to explore whether attenuated negative symptoms mediated the relationship between interpersonal sensitivity and social functioning. Individuals with UHR state showed higher IPSM scores and lower GF:SS and GF:RS scores than NS participants. A statistically negative significant correlation between two IPSM subscales (Interpersonal Awareness and Timidity) and GF:SS was found in both groups. Our results also suggest that the relationship between the aforementioned aspects of interpersonal sensitivity and social functioning was not mediated by negative prodromal symptoms. This study suggests that some aspects of interpersonal sensitivity were associated with low level of social functioning. Assessing and treating interpersonal sensitivity may be a promising therapeutic target to improve social functioning in young help-seeking individuals.
一种常常引发不良和不安人际关系的人格特质是人际敏感性。本研究的目的是探讨人际敏感性与处于精神病超高风险的个体的心理社会功能之间的关系，并与筛查出精神病超高风险呈阴性的求助个体进行比较。共有147名因出现心理健康问题而寻求帮助的青少年和青年参与了该研究。样本被分为两组：39名符合超高风险精神状态（UHR）标准的个体，以及108名（非超高风险组，NS）。整个样本完成了人际敏感性量表（IPSM）和总体功能：社会和角色量表（GF:SS；GF:RS）。中介分析用于探讨减弱的阴性症状是否介导了人际敏感性与社会功能之间的关系。处于UHR状态的个体比非超高风险组参与者表现出更高的IPSM得分以及更低的GF:SS和GF:RS得分。在两组中均发现两个IPSM子量表（人际意识和羞怯）与GF:SS之间存在统计学上的显著负相关。我们的结果还表明，人际敏感性的上述方面与社会功能之间的关系并非由前驱期阴性症状介导。本研究表明，人际敏感性的某些方面与低水平的社会功能相关。评估和治疗人际敏感性可能是改善年轻求助个体社会功能的一个有前景的治疗靶点。
