Cain G R, Champlin R E
Laboratory for Energy-Related Health Research, University of California, Davis 95616.
Am J Vet Res. 1989 Aug;50(8):1282-4.
Karyotype analysis of bone marrow cells was performed from 6 Beagles that had received sex-mismatched fetal liver hematopoietic stem cell grafts 2.4 to 6.5 years earlier. Two dogs received dog leukocyte antigen-matched fetal liver cells and 4 received dog leukocyte antigen-mismatched cells. In each dog, all 25 evaluated metaphase spreads were of donor genotype. All dogs had normal hemograms and repopulation of bone marrow and no dog developed graft-vs-host disease.
对6只比格犬进行了骨髓细胞的核型分析，这些比格犬在2.4至6.5年前接受了性别不匹配的胎儿肝脏造血干细胞移植。2只犬接受了犬白细胞抗原匹配的胎儿肝脏细胞，4只犬接受了犬白细胞抗原不匹配的细胞。每只犬的所有25个评估中期分裂相均为供体基因型。所有犬的血常规和骨髓再填充均正常，且无犬发生移植物抗宿主病。
