Hospital de Emergencias Psiquiatricas Torcuato de Alvear, Av Warnes 2630, Capital Federal, Argentina ; Bipolar Disorder Program, Neurosciences Institute, Favaloro University, Buenos Aires, Argentina.
Hospital de Emergencias Psiquiatricas Torcuato de Alvear, Av Warnes 2630, Capital Federal, Argentina.
Int J Bipolar Disord. 2015 Feb 24;3:4. doi: 10.1186/s40345-014-0020-y. eCollection 2015.
There is an increasing use of ayahuasca for recreational purposes. Furthermore, there is a growing evidence for the antidepressant properties of its components. However, there are no reports on the effects of this substance in the psychiatric setting. Harmaline, one of the main components of ayahuasca, is a selective and reversible MAO-A inhibitor and a serotonin reuptake inhibitor.
We present the case of a man with bipolar disorder who had a manic episode after an ayahuasca consumption ritual. This patient had had at least one hypomanic episode in the past and is currently depressed. We discuss the diagnostic repercussion of this manic episode.
There is lack of specificity in the diagnosis of substance-induced mental disorder. The knowledge of the pharmacodynamic properties of ayahuasca consumption allows a more physiopathological approach to the diagnosis of the patient.
越来越多的人出于娱乐目的而使用死藤水。此外，其成分具有抗抑郁作用的证据也越来越多。然而，在精神科环境中，尚无关于这种物质的影响的报告。哈他胺是死藤水的主要成分之一，是一种选择性和可逆的 MAO-A 抑制剂和 5-羟色胺再摄取抑制剂。
我们介绍了一位患有双相情感障碍的男性，在进行死藤水摄入仪式后出现躁狂发作。该患者过去至少有过一次轻躁狂发作，目前处于抑郁状态。我们讨论了此次躁狂发作的诊断影响。
物质引起的精神障碍的诊断缺乏特异性。对死藤水摄入的药效学特性的了解，使得对患者的诊断可以采用更具生理病理特性的方法。
