Zhang Jie, Shao Ying, Wang Yaxiong, Li Huihuang, Xu Dongmei, Wan Xiaobing
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Renai Road, 215123 Suzhou, China.
Org Biomol Chem. 2015 Apr 7;13(13):3982-7. doi: 10.1039/c5ob00109a.
A transition-metal-free decarboxylation coupling process for the preparation of α-amino acid esters, which succeeded in merging hydrolysis/decarboxylation/nucleophilic substitution, is well described. This strategy uses commercially available inexpensive starting materials, catalysts and oxidants and has a wide substrate scope and operational simplicity.
一种用于制备α-氨基酸酯的无过渡金属脱羧偶联方法得到了很好的描述，该方法成功地将水解/脱羧/亲核取代结合在一起。此策略使用市售的廉价起始原料、催化剂和氧化剂，具有广泛的底物范围且操作简便。
