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1
Prophylactic antibiotics for children with recurrent urinary tract infections.复发性尿路感染儿童的预防性抗生素治疗。
Paediatr Child Health. 2015 Jan-Feb;20(1):45-51. doi: 10.1093/pch/20.1.45.
2
Susceptibility of the Index Urinary Tract Infection to Prophylactic Antibiotics Is a Predictive Factor of Breakthrough Urinary Tract Infection in Children with Primary Vesicoureteral Reflux Receiving Continuous Antibiotic Prophylaxis.预防性抗生素对索引性尿路感染的敏感性是接受持续抗生素预防的原发性膀胱输尿管反流患儿突破性尿路感染的预测因素。
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Antibiotic prophylaxis in pediatric urology.小儿泌尿外科中的抗生素预防
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Antibiotic resistance patterns of community-acquired urinary tract infections in children with vesicoureteral reflux receiving prophylactic antibiotic therapy.接受预防性抗生素治疗的膀胱输尿管反流患儿社区获得性尿路感染的抗生素耐药模式
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Is antibiotic prophylaxis effective in preventing urinary tract infections in patients with vesicoureteral reflux?抗生素预防疗法在预防伴有膀胱输尿管反流的患者尿路感染方面是否有效？
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Interventions for primary vesicoureteric reflux.原发性膀胱输尿管反流的干预措施。
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Long-term antibiotics for preventing recurrent urinary tract infection in children.长期使用抗生素预防儿童复发性尿路感染
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Long-term antibiotics for the prevention of recurrent urinary tract infection in children: a systematic review and meta-analysis.长期使用抗生素预防儿童复发性尿路感染：系统评价和荟萃分析。
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Risk Factors for Recurrent Urinary Tract Infection and Renal Scarring.复发性尿路感染和肾瘢痕形成的危险因素。
Pediatrics. 2015 Jul;136(1):e13-21. doi: 10.1542/peds.2015-0409. Epub 2015 Jun 8.

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Guidelines for Complicated Urinary Tract Infections in Children: A Review by the European Society for Pediatric Infectious Diseases.儿童复杂性尿路感染指南：欧洲儿科传染病学会综述
Pediatr Infect Dis J. 2025 Jun 1;44(6):e211-e223. doi: 10.1097/INF.0000000000004790. Epub 2025 Mar 19.
2
Quality indicators for appropriate antibiotic prescribing in urinary tract infections in children.儿童尿路感染中抗生素使用适宜性的质量指标。
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3
Assessing nephrology competence in general paediatrics-A survey of general paediatricians, paediatric nephrologists, residents, and program directors.评估普通儿科中的肾脏病学能力——一项针对普通儿科医生、儿科肾脏病学家、住院医师和项目主任的调查。
Paediatr Child Health. 2021 Nov 30;27(3):169-175. doi: 10.1093/pch/pxab089. eCollection 2022 Jun.
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Diagnosis and management of community-acquired urinary tract infection in infants and children: Clinical guidelines endorsed by the Saudi Pediatric Infectious Diseases Society (SPIDS).婴幼儿社区获得性尿路感染的诊断与管理：沙特儿科传染病学会（SPIDS）认可的临床指南
Int J Pediatr Adolesc Med. 2021 Jun;8(2):57-67. doi: 10.1016/j.ijpam.2021.03.001. Epub 2021 Mar 11.
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Urinary Tract Infection in Children.儿童尿路感染
Recent Pat Inflamm Allergy Drug Discov. 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940.
6
A critical review of recent clinical practice guidelines for pediatric urinary tract infection.对近期儿童尿路感染临床实践指南的批判性综述。
Can Urol Assoc J. 2018 Apr;12(4):112-118. doi: 10.5489/cuaj.4796. Epub 2017 Dec 22.

本文引用的文献

1
Urinary tract infections in infants and children: Diagnosis and management.婴幼儿尿路感染：诊断与管理
Paediatr Child Health. 2014 Jun;19(6):315-25. doi: 10.1093/pch/19.6.315.
2
Antimicrobial prophylaxis for children with vesicoureteral reflux.膀胱输尿管反流患儿的抗菌预防
N Engl J Med. 2014 Sep 11;371(11):1071-2. doi: 10.1056/NEJMc1408559.
3
Antimicrobial prophylaxis for children with vesicoureteral reflux.小儿膀胱输尿管反流的抗菌预防。
N Engl J Med. 2014 Jun 19;370(25):2367-76. doi: 10.1056/NEJMoa1401811. Epub 2014 May 4.
4
Denominators do matter: it's a myth--urinary tract infection does not cause chronic kidney disease.分母很重要：这是个误区——尿路感染不会导致慢性肾病。
Pediatrics. 2011 Nov;128(5):984-5. doi: 10.1542/peds.2011-2631. Epub 2011 Oct 10.
5
Technical report—Diagnosis and management of an initial UTI in febrile infants and young children.技术报告——发热婴儿和幼儿初始尿路感染的诊断和治疗。
Pediatrics. 2011 Sep;128(3):e749-70. doi: 10.1542/peds.2011-1332. Epub 2011 Aug 28.
6
Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months.尿路感染：发热婴儿和儿童（2 至 24 个月）初始尿路感染的诊断和管理临床实践指南。
Pediatrics. 2011 Sep;128(3):595-610. doi: 10.1542/peds.2011-1330. Epub 2011 Aug 28.
7
Long-term antibiotics for preventing recurrent urinary tract infection in children.长期使用抗生素预防儿童复发性尿路感染
Cochrane Database Syst Rev. 2011 Mar 16(3):CD001534. doi: 10.1002/14651858.CD001534.pub3.
8
Antibiotic prophylaxis and recurrent urinary tract infection in children.儿童抗生素预防与复发性尿路感染
N Engl J Med. 2009 Oct 29;361(18):1748-59. doi: 10.1056/NEJMoa0902295.
9
Prevention of recurrent urinary tract infection in children.儿童复发性尿路感染的预防
Curr Opin Infect Dis. 2009 Feb;22(1):72-6. doi: 10.1097/QCO.0b013e328320a885.
10
Prophylaxis after first febrile urinary tract infection in children? A multicenter, randomized, controlled, noninferiority trial.儿童首次发热性尿路感染后的预防措施？一项多中心、随机、对照、非劣效性试验。
Pediatrics. 2008 Nov;122(5):1064-71. doi: 10.1542/peds.2007-3770.

复发性尿路感染儿童的预防性抗生素治疗。

Prophylactic antibiotics for children with recurrent urinary tract infections.

作者信息

Robinson Joan L, Finlay Jane C, Lang Mia Eileen, Bortolussi Robert

出版信息

Paediatr Child Health. 2015 Jan-Feb;20(1):45-51. doi: 10.1093/pch/20.1.45.

DOI:10.1093/pch/20.1.45
PMID:25722643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4333755/
Abstract

Prophylactic antibiotics for urinary tract infections are no longer routinely recommended. A large number of children must be given prophylaxis to prevent one infection and antibiotic resistance is a major concern when treating community-acquired urinary tract infections. The results of three recent significant studies are examined, with focus on the efficacy of prophylaxis, and recommendations are made.

摘要

不再常规推荐使用预防性抗生素来治疗尿路感染。必须对大量儿童进行预防以防止一次感染，而在治疗社区获得性尿路感染时，抗生素耐药性是一个主要问题。本文审视了最近三项重要研究的结果，重点关注预防的效果，并给出了相关建议。