Chaney Amanda
Department of Transplant, Mayo Clinic, Jacksonville, Florida.
J Am Assoc Nurse Pract. 2015 Aug;27(8):415-9. doi: 10.1002/2327-6924.12217. Epub 2015 Feb 26.
Vitamin D deficiency is one of the most common medical conditions. Up to 96% of patients with liver disease have this deficiency. The purpose of this manuscript is to educate primary care nurse practitioners (NPs) of vitamin D deficiency and its proper management in patients with liver disease.
Information was compiled by reviewing the scientific literature on cirrhosis, liver disease, and vitamin D deficiency (CINAHL, MEDLINE, PubMed search engines).
While the usual supplement dose for vitamin D deficiency is 1000 international units (vitamin D3 ) daily, vitamin D2 supplementation at doses of 50,000 international units can be given for correction. Primary care NPs can assist patients with liver disease with optimal nutrition and vitamin supplementation.
Primary care NPs should be aware of vitamin D deficiency in patients with liver disease. Vitamin D supplementation may be required in high doses in those patients with a moderate to severe deficiency. Repeat 25-hydroxyvitamin D levels should be checked after supplementation is completed and yearly thereafter.
维生素D缺乏是最常见的病症之一。高达96%的肝病患者存在这种缺乏情况。本手稿的目的是对初级保健执业护士进行有关维生素D缺乏及其在肝病患者中的正确管理的教育。
通过查阅关于肝硬化、肝病和维生素D缺乏的科学文献（CINAHL、MEDLINE、PubMed搜索引擎）汇编信息。
虽然维生素D缺乏的常规补充剂量是每日1000国际单位（维生素D3），但可以给予50000国际单位剂量的维生素D2进行纠正。初级保健执业护士可以帮助肝病患者实现最佳营养和维生素补充。
初级保健执业护士应了解肝病患者中的维生素D缺乏情况。对于中度至重度缺乏的患者可能需要高剂量补充维生素D。补充完成后应检查25-羟基维生素D水平，之后每年检查一次。
