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一项关于盐酸异丙嗪与喷他佐辛肌内注射镇静联合2%盐酸利多卡因和肾上腺素,并与安慰剂联合2%盐酸利多卡因和肾上腺素用于下颌第三磨牙手术拔除的研究。

A study of promethazine hydrochloride and pentazocine intramuscular sedation along with 2 % lidocaine hydrochloride and adrenaline and comparison to placebo along with 2 % lidocaine hydrochloride and adrenaline for surgical extraction of mandibular third molar.

作者信息

Lalfamkima F, Debnath Subhas Chandra, Adhyapok A K

机构信息

Department of Oral and Maxillofacial Surgery, Regional Dental College, Guwahati, 781005 Assam India.

Department of Oral and Maxillofacial Surgery, Regional Dental College, Guwahati, 781005 Assam India ; Sai Dental Clinic and Facio-Maxillary Surgery Centre, Rajgarh Road, Bhangagarh, Opposite Alcare Diagnostic Centre, House No. 148, Guwahati, 781005 Assam India.

出版信息

J Maxillofac Oral Surg. 2015 Mar;14(1):90-100. doi: 10.1007/s12663-013-0595-3. Epub 2013 Nov 30.

Abstract

BACKGROUND AND OBJECTIVES

The main objective is to study and compare the sedative and analgesic effects of intramuscular injection fortwin-phenergan along with local anesthetic and normal saline placebo along with local anesthetics in mandibular third molar surgery. We also assessed and compared the postoperative experience of the patient in relation to the pain intensity, time to first analgesic taken and total number of analgesics consumed over a period of 48 h in the two groups.

MATERIALS AND METHODS

Patients who came to the Department of Oral and Maxillofacial Surgery, The Regional Dental College; with complaints regarding mandibular third molar were chosen for the treatment. Patients were evaluated using Corah Dental Anxiety Scale (CDAS) and those patients having a score of CDAS 13 and above were selected. Sixty patients were selected out of which 30 patients formed group 1 and another 30 patients group 2. The patients were randomly divided with flip method into group 1 (study group) and or group 2 (controlled group).

RESULTS

Our study results showed that the operating conditions for both the groups at the end of surgery were similar without significant difference. Most of the surgical procedures were graded as excellent and good in both the groups except that difficulty was encountered in two patients from group 1 and one from group 2.

CONCLUSION

It could be concluded that particular drugs do not have much influence on the surgical procedure in our study, but it was found that patients from group 1 were more cooperative as compared to group 2 when difficulty was encountered during the surgical procedure.

摘要

背景与目的

主要目的是研究并比较在下颌第三磨牙手术中,肌肉注射氟哌利多 - 异丙嗪联合局部麻醉剂与生理盐水安慰剂联合局部麻醉剂的镇静和镇痛效果。我们还评估并比较了两组患者在术后48小时内的疼痛强度、首次服用镇痛药的时间以及镇痛药的总消耗量等方面的体验。

材料与方法

选择到地区牙科学院口腔颌面外科就诊、主诉下颌第三磨牙相关问题的患者进行治疗。使用科拉牙科焦虑量表(CDAS)对患者进行评估,选择CDAS评分在13分及以上的患者。从这些患者中选出60例,其中30例患者组成第1组,另外30例患者组成第2组。通过抛硬币法将患者随机分为第1组(研究组)和第2组(对照组)。

结果

我们的研究结果表明,手术结束时两组的手术条件相似,无显著差异。除了第1组有2例患者和第2组有1例患者遇到困难外,两组的大多数手术操作等级均为优秀和良好。

结论

可以得出结论,在我们的研究中特定药物对手术操作影响不大,但发现在手术过程中遇到困难时,第1组患者比第2组患者更配合。

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Oral sedation: a primer on anxiolysis for the adult patient.口服镇静:成年患者抗焦虑治疗入门
Anesth Prog. 2007 Fall;54(3):118-28; quiz 129. doi: 10.2344/0003-3006(2007)54[118:OSAPOA]2.0.CO;2.

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